The Kingsley Clinic

Digestive

Isosorbide Dinitrate: Uses, Dosage, and Side Effects

US Brand Name: {Isordil}, {Dilatrate-SR} (Isosorbide Dinitrate) Pharmacologic Category: {Nitrates} Other medications in the same pharmacologic category: {Nitroglycerin}, {Isosorbide mononitrate}, and {Amyl nitrite}. Diseases Treated, Dosing, and Treatment Duration: {Stable angina pectoris}: 5-20 mg sublingually or orally every 5-6 hours, up to 120 mg/day in divided doses {Unstable angina}: 5-20 mg sublingually or orally every …

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Understanding Aortic Stenosis: Symptoms, Causes, and Treatment Options

Understanding Aortic Stenosis: Symptoms, Causes, and Treatment Options Introduction Aortic stenosis is a common heart condition that affects the aortic valve, the gateway between the left ventricle and the aorta. This article aims to provide a comprehensive overview of aortic stenosis, including its definition, risk factors, clinical manifestations, differential diagnosis, diagnostic evaluation, and treatment options. …

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Clopidogrel (Plavix) – Uses, Dosage, Side Effects, and More

US Brand Name: Plavix (Clopidogrel) Pharmacologic Category: Antiplatelet Agent Other medications in the same category: {Aspirin}, {Ticagrelor} (Brilinta), {Prasugrel} (Effient), {Dipyridamole} (Persantine) Diseases Treated, Dosing, and Treatment Duration: {Acute Coronary Syndrome (ACS)}: 300 mg loading dose, followed by 75 mg daily for up to 12 months. {Myocardial Infarction (MI)}: 75 mg daily for up to …

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Understanding Aortic Regurgitation: Symptoms, Causes, Diagnosis, and Treatment

Understanding Aortic Regurgitation: Symptoms, Causes, Diagnosis, and Treatment Options Introduction Aortic regurgitation is a heart condition characterized by the backward flow of blood from the aorta into the left ventricle, due to a malfunctioning {aortic valve}. This article aims to provide comprehensive information about aortic regurgitation, including its definition, risk factors, clinical manifestations, differential diagnosis, …

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Simvastatin Medication Profile: Uses, Side Effects, and Dosing

Simvastatin Medication Profile: Uses, Side Effects, and Dosing Names of Medication US Brand Name: Zocor ({Simvastatin}) 2. Pharmacologic Category HMG-CoA Reductase Inhibitors (Statins) Other medications in the same pharmacologic category: Atorvastatin, Rosuvastatin, Pravastatin, Lovastatin, Fluvastatin, and Pitavastatin. 3. Diseases Treated, Dosing, and Treatment Duration {Primary hypercholesterolemia (high cholesterol)}: 5-40 mg orally once daily {Mixed dyslipidemia}: …

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Ezetimibe (Zetia) – Uses, Dosage, Side Effects and More

US Brand Name: Zetia (Ezetimibe) Pharmacologic Category: Cholesterol Absorption Inhibitor Diseases Treated, Dosing, and Treatment Duration: {Primary hypercholesterolemia (high cholesterol)}: 10 mg once daily {Mixed dyslipidemia}: 10 mg once daily {Familial hypercholesterolemia}: 10 mg once daily {Homozygous familial sitosterolemia (phytosterolemia)}: 10 mg once daily Dosage Forms and Strengths: Tablets: 10 mg Administration Instructions: {Ezetimibe} can …

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Evolocumab (Repatha) – Uses, Dosage, Side Effects and More

US Brand Name: Repatha (Evolocumab) Pharmacologic Category: Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) Inhibitor Other medications in this category: {Alirocumab} (Praluent) Diseases Treated, Dosing, and Treatment Duration: {Heterozygous familial hypercholesterolemia (HeFH)}: 140 mg every 2 weeks or 420 mg once monthly {Homozygous familial hypercholesterolemia (HoFH)}: 420 mg once monthly {Clinical atherosclerotic cardiovascular disease (ASCVD)} requiring …

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Alirocumab (Praluent) – Uses, Dosage, Side Effects, and More

US Brand Name (Generic Name): Praluent (alirocumab) Pharmacologic Category: PCSK9 inhibitor Other medications in the same category include: {Evolocumab} (Repatha) Diseases Treated and Dosing Information: {Heterozygous familial hypercholesterolemia (HeFH)}: Initial dose is 75 mg every 2 weeks; can be increased to 150 mg every 2 weeks if needed for additional LDL cholesterol reduction. {Homozygous familial …

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Effient (Prasugrel) – Uses, Dosage, and Side Effects

US Brand Name: Effient (Prasugrel) Pharmacologic category: {Antiplatelet agent}, P2Y12 platelet inhibitor. Other medications in the same pharmacologic category include: {Plavix} (Clopidogrel), {Brilinta} (Ticagrelor). Diseases Treated, Dosing, and Treatment Duration {Acute coronary syndrome} (ACS): 60 mg loading dose, followed by 10 mg daily. Duration of treatment depends on the clinical condition and physician’s recommendation. {Unstable …

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Ticagrelor (Brilinta): Uses, Side Effects, and Interactions

US Brand Name: {Brilinta} ({Ticagrelor}) Pharmacologic category: {P2Y12 platelet inhibitors} Other medications in the same pharmacologic category include: {Plavix} ({Clopidogrel}), {Effient} ({Prasugrel}) Diseases Treated, Dosing, and Treatment Duration {Acute coronary syndrome} (ACS): 180 mg loading dose, followed by 90 mg twice daily for up to 12 months {Unstable angina}: Same as for ACS {Non-ST-segment elevation …

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