US Brand Name (Generic Name): Calan, Verelan, Covera-HS (Verapamil)
Pharmacologic Category:
{Calcium channel blockers}. Other medications in the same category include {diltiazem}, {nifedipine}, {amlodipine}, and {nicardipine}.
Diseases Treated, Dosing, and Treatment Duration:
{Hypertension}: The usual dose of Verapamil for hypertension is 80 mg to 120 mg taken orally, three times daily. The maximum daily dose is 480 mg.
{Angina pectoris}: The usual dose of Verapamil for angina pectoris is 80 mg to 120 mg taken orally, three times daily. The maximum daily dose is 480 mg.
{Supraventricular tachycardia}: The usual dose of Verapamil for supraventricular tachycardia is 240 mg to 480 mg taken orally, divided into multiple doses per day.
{Atrial fibrillation/flutter}: The usual dose of Verapamil for atrial fibrillation/flutter is 240 mg to 480 mg taken orally, divided into multiple doses per day.
{Cluster headaches}: The usual dose of Verapamil for cluster headaches is 240 mg to 480 mg taken orally, divided into multiple doses per day.
{Migraine headaches}: The usual dose of Verapamil for migraine headaches is 240 mg to 480 mg taken orally, divided into multiple doses per day.
{Raynaud’s phenomenon}: The usual dose of Verapamil for Raynaud’s phenomenon is 240 mg to 480 mg taken orally, divided into multiple doses per day.
Dosage Forms and Strengths:
Tablets: 40 mg, 80 mg, 120 mg, 180 mg Capsules: 100 mg, 200 mg, 300 mg Extended-release tablets: 120 mg, 180 mg, 240 mg, 360 mg
Administration Instructions:
It can be taken with or without food, but should be taken consistently with regards to meals. Verapamil should be swallowed whole with a full glass of water and should not be crushed or chewed.
Adverse Reactions and Side Effects:
Common side effects of Verapamil include {constipation}, {headache}, {dizziness}, {nausea}, and {edema}. Less common but more serious side effects include {low blood pressure}, {heart block}, and {liver damage}.
Contraindications:
Verapamil is contraindicated in patients with severe {hypotension}, {sick sinus syndrome}, second- or third-degree {AV block}, and severe {left ventricular dysfunction}. It should also be used with caution in patients with {hepatic} or {renal impairment}, as well as in patients taking other medications that may interact with Verapamil.
Drug to Drug Interactions:
{Beta-blockers} ({propranolol}) {Digoxin} {Statins} ({atorvastatin}, {simvastatin}) {CYP3A4 inhibitors} ({ketoconazole}, {itraconazole}, {erythromycin}, {clarithromycin}, {nefazodone}, {diltiazem})
Is this medication safe to take when pregnant?
It is not well established, and it should only be used if the potential benefits outweigh the potential risks to the fetus.
Is this medication safe to take when breastfeeding?
It is excreted in breast milk, and its use during breastfeeding is not recommended.
Estimated price of a 30-day supply of the medication assuming the patient doesn’t have insurance and is utilizing a GoodRx coupon:
The price of Verapamil can vary depending on the pharmacy and the strength of the medication. With a GoodRx coupon, a 30-day supply of Verapamil can cost between $12 to $40, depending on the strength and pharmacy. It’s important to note that prices may vary depending on the region and the pharmacy.
Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.