Sulfapyridine: An Essential Guide
Summary or Key Points
Sulfapyridine, a sulfonamide antibiotic, is a medication used primarily in treating rheumatoid arthritis, ulcerative colitis, Crohn’s disease, and systemic lupus erythematosus. It helps by reducing inflammation and bacterial growth. This article provides a detailed overview of the medication, including dosages, side effects, contraindications, and potential interactions.
Names of Medication
Brand Name: No common brand names are available in the US.
Generic Name: Sulfapyridine (SUL fa PIR i deen)
A medication’s ‘generic name’ is its standard scientific name, not tied to any specific brand or manufacturer. Here, the generic name is provided in parentheses.
Pharmacologic Category
Sulfonamide Antibiotics.
Dosing
The dosage of Sulfapyridine varies depending on the condition it’s used to treat. Here are common uses:
- Rheumatoid Arthritis: 2g to 4g daily, divided into 4-6 doses.
- Ulcerative Colitis: 1g to 2g daily, divided into 3-4 doses.
- Crohn’s Disease: Dosage is determined on a case-by-case basis.
- Systemic Lupus Erythematosus (SLE): Dosage is determined on a case-by-case basis.
Always consult your healthcare provider for specific dosing instructions and before adjusting your dose. If you are interested in discussing your treatment plan, schedule an appointment with one of our telemedicine providers today.
Dosage Forms and Strengths
Sulfapyridine is most commonly available as 500 mg oral tablets.
Administration Instructions
Take this medication by mouth, usually 3 to 4 times daily or as directed by your healthcare provider. It should be taken with a full glass of water and may be taken with food or milk if stomach upset occurs. Your dosage is based on your medical condition and response to therapy.
Adverse Reactions and Side Effects
Common side effects of Sulfapyridine can include:
- Nausea or vomiting: Feeling sick or throwing up (Very Common).
- Headache: Pain in the head area (Common).
- Rash: Skin reactions like rashes, itching, and hives (Uncommon).
- Changes in blood counts: Reduced white or red blood cell count, leading to increased infection risk or tiredness (Rare).
If you notice any of these side effects, contact your healthcare provider or one of our telemedicine providers right away.
Contraindications
Contraindications’ are conditions or factors that serve as reasons not to take a certain medication due to the harm it could cause. Sulfapyridine is contraindicated in:
- People with known hypersensitivity to sulfonamides: Because it may cause severe allergic reactions.
- People with certain blood disorders (porphyria, glucose-6-phosphate dehydrogenase deficiency): Due to the risk of triggering a crisis.
Drug to Drug Interactions
Some medications that may interact with Sulfapyridine include:
- Methotrexate (Rheumatrex, Trexall): The combination can increase the risk of side effects.
- Warfarin (Coumadin): Sulfapyridine can enhance the effect of warfarin, increasing the risk of bleeding.
- Phenytoin (Dilantin): The combination can increase the blood levels of phenytoin, potentially increasing its side effects.
Remember to inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal products.
Sulfapyridine in Pregnancy
Studies on the use of Sulfapyridine during pregnancy are limited. The drug should only be used if the benefits outweigh the risks. Always consult with your healthcare provider if you are pregnant or planning to become pregnant while taking this medication.
Sulfapyridine while Breastfeeding
Sulfapyridine passes into breast milk and may have undesirable effects on a nursing infant. It’s important to discuss the risks and benefits with your healthcare provider before taking this medication while breastfeeding.
Estimated Cost of Medication
The cost for Sulfapyridine oral tablet 500 mg can range from $40 to $60 for a 30-day supply, depending on the pharmacy you visit. Prices are for cash-paying customers using a GoodRx coupon and are not valid with insurance plans.
Possible Alternatives
Other treatments are available for the conditions that Sulfapyridine is used to treat. Always discuss these options with your healthcare provider before making changes to your treatment plan. Possible alternatives include:
- Rheumatoid Arthritis: Nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, disease-modifying antirheumatic drugs (DMARDs), and biologic response modifiers.
- Ulcerative Colitis: Aminosalicylates, corticosteroids, immunomodulators, and biologics.
- Crohn’s Disease: Aminosalicylates, corticosteroids, immunomodulators, antibiotics, and biologics.
- Systemic Lupus Erythematosus (SLE): NSAIDs, corticosteroids, antimalarials, and immunosuppressives.
Recent Updates on Sulfapyridine Research
Research on Sulfapyridine is ongoing. Recent studies have examined its potential use in the treatment of other autoimmune conditions. As of now, it is primarily used for the treatment of rheumatoid arthritis and certain gastrointestinal conditions. Always consult your healthcare provider for the most recent and relevant information.
Remember, our telemedicine providers are readily available to address your concerns and questions about Sulfapyridine or any other health-related topics. Please schedule an appointment with us at your convenience.
Brief Legal Disclaimer
This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.
While every effort has been made to ensure the accuracy of this information, medicine is a constantly evolving field, and changes may occur that may not be reflected here. Please discuss any concerns or questions you have about your health or medications with your healthcare provider.
Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.