Medication Profile: Raloxifene

Summary or Key Points

Raloxifene is a medication primarily used to treat and prevent osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer. As an estrogen agonist/antagonist, it strengthens bones and decreases the risk of fractures, while also blocking the effects of estrogen in the breast tissue. As with any medication, it is crucial to discuss any concerns or questions with your healthcare provider. Through our telemedicine services, professional help is readily available to you.

Names of Medication

The US Brand Name for this medication is Evista, with Raloxifene being the generic name. The term ‘generic name’ refers to the official medical name for the active ingredient of the medicine, which is listed in parenthesis.

Pharmacologic Category

Raloxifene is a Selective Estrogen Receptor Modulator (SERM). Other medications in this category include Tamoxifen and Toremifene.

Dosing

Raloxifene is indicated to treat the following conditions in adults:

• Postmenopausal osteoporosis: 60 mg orally once daily.
• Reduction in risk of invasive breast cancer: 60 mg orally once daily.

Please consult with your healthcare provider before adjusting your dose. Our telemedicine services are always available for consultation.

Dosage Forms and Strengths

Raloxifene is available in a tablet form and comes in one strength, 60 mg.

Administration Instructions

Raloxifene is usually taken once a day, with or without food. Try to take the medication at the same time each day. If a dose is missed, take it as soon as possible unless it is almost time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule.

Adverse Reactions and Side Effects

Common side effects of Raloxifene may include hot flashes, leg cramps, swelling, and flu-like symptoms. More serious side effects, though less common, can include blood clots and stroke. Always seek immediate medical attention if you experience severe side effects.

Contraindications

A contraindication is a situation in which a drug should not be used because it may be harmful to the patient. Raloxifene is contraindicated in individuals with a history of blood clots, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis. It is also contraindicated in women who are or may become pregnant, as it may harm the fetus.

Drug to Drug Interactions

Raloxifene can interact with several other medications. Some of these include:

• Cholestyramine (Prevalite)
• Clofibrate (Atromid-S)
• Estrogens (Premarin, Estrace)

Always inform your healthcare provider about all the medications you are taking.

Raloxifene in Pregnancy

Raloxifene is not recommended for use during pregnancy. It may harm an unborn baby. If you become pregnant or plan to become pregnant while taking Raloxifene, contact your healthcare provider immediately.

Raloxifene while Breastfeeding

It is not known whether Raloxifene passes into breast milk. However, due to potential risks to the nursing infant, it is advised to avoid breastfeeding while taking this medication.

Estimated Cost of Medication

As of the date of this article, the estimated cost of a 30-day supply of Raloxifene (generic Evista) is approximately $40 to $60 without insurance, using a GoodRx coupon. Prices may vary based on the pharmacy and location.

Possible Alternatives

Alternatives for osteoporosis include bisphosphonates such as Alendronate (Fosamax) or lifestyle changes like weight-bearing exercise, adequate calcium and vitamin D intake. Alternatives for reducing the risk of invasive breast cancer may include other SERMs like Tamoxifen or aromatase inhibitors. Always consult with your healthcare provider before making any changes to your treatment plan. Our telemedicine services can provide immediate consultation.

Recent Updates on Raloxifene Research

Recent studies suggest Raloxifene may have a role in preventing cognitive decline in postmenopausal women, but more research is needed to confirm these findings. Other ongoing studies are looking into Raloxifene’s potential in reducing the risk of heart disease.

Remember to consult with your healthcare provider or our telemedicine services for any concerns or queries regarding Raloxifene. Information is continuously updated, and your health is our priority.

Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.