Colestipol: An Essential Guide to Usage, Dosage, and Side Effects

Summary or Key Points

Colestipol (Colestid) is a medication primarily used to treat high cholesterol levels, pruritus (itching) associated with partial biliary obstruction, and diarrhea caused by bile acid malabsorption. It works by binding bile acids in your intestines to help remove them from your body. As with any medication, it’s crucial to understand its uses, dosages, and potential side effects. Always consult with your healthcare provider before making any changes to your medication regimen. Our telemedicine team is readily available to help you navigate your treatment plan.

Names of Medication

Colestid (Colestipol)

In healthcare, medications often have two names: a brand name and a generic name. The brand name is the trade name given by the manufacturer, while the generic name describes the drug’s active ingredient. In this article, the generic name is always included in parenthesis.

Pharmacologic Category

Colestipol belongs to a class of drugs known as bile acid sequestrants. Other medications in this category include Cholestyramine (Questran, Prevalite) and Colesevelam (Welchol).

Dosing

Hypercholesterolemia (High cholesterol): The typical dose for adults is 2-16 grams/day taken in one or two doses. The dosage can be adjusted based on the patient’s cholesterol levels.

Pruritus associated with Partial Biliary Obstruction: The usual adult dosage is 2-16 grams/day. The doctor might adjust the dosage based on the patient’s symptoms and response to treatment.

Diarrhea due to Bile Acid Malabsorption: The dose for adults is typically 2-16 grams/day, which can be adjusted based on the individual’s symptoms and response to the medication.

Remember, these are standard dosages and can vary based on individual health conditions and responses to the medication. Always consult with your healthcare provider before adjusting your dose. Our providers are available for telemedicine consultations to discuss your treatment plan and any concerns you may have.

Dosage Forms and Strengths

Colestipol is available in the following forms and strengths:

• Tablets: 1 gram
• Powder for oral suspension: 5 grams/packet, 5 grams/teaspoon

Administration Instructions

Colestipol should be taken as directed by your healthcare provider. It can be taken with or without food. If you are taking the powder form, mix it with water, non-carbonated beverages, or a soft food like applesauce or crushed pineapple. Do not take it in its dry form. Always drink plenty of fluids when taking this medication.

Adverse Reactions and Side Effects

Colestipol is generally well-tolerated, but like all medications, it may have some side effects. These can include:

• Common: Constipation, abdominal pain, or bloating.
• Less common: Nausea, heartburn, or indigestion.
• Rare: Vomiting, hemorrhoids, or blood in

  the stool.

If you experience any of these symptoms or other side effects, it’s essential to consult your healthcare provider immediately. Our telemedicine team is readily available to help address any concerns or symptoms you may be experiencing.

Contraindications

A contraindication is a specific situation or condition that makes it unsafe to take a particular medication. For Colestipol, contraindications include:

• Total Biliary Obstruction: Colestipol works by binding to bile acids in the intestine. However, if there is a complete obstruction in the bile duct, it could lead to an excessive buildup of bile acids.

Before starting Colestipol, inform your healthcare provider about all existing health conditions. Our telemedicine providers are available to discuss any concerns you may have.

Drug to Drug Interactions

Certain medications can interact with Colestipol, affecting its effectiveness or increasing the risk of side effects. These include:

• Digoxin (Lanoxin)
• Warfarin (Coumadin, Jantoven)
• Thyroid hormones like levothyroxine (Synthroid, Levoxyl, Tirosint, Unithroid)

Colestipol in Pregnancy

Colestipol is considered generally safe to use during pregnancy under the guidance of a healthcare provider. However, every individual’s health scenario is different. If you are pregnant or plan to become pregnant, it’s essential to discuss this with your healthcare provider, and our telemedicine team is available to assist you.

Colestipol while Breastfeeding

It is not known whether Colestipol passes into breast milk. If you are breastfeeding, consult your healthcare provider before starting this medication. Our telemedicine team can provide guidance and support.

Estimated Cost of Medication

As of the date of this article, the estimated cost for a 30-day supply of Colestipol using a GoodRX coupon is approximately $40-60. Prices may vary depending on the pharmacy and location.

Possible Alternatives

Alternatives to Colestipol include other medications, dietary changes, and lifestyle adjustments. However, these should only be considered after discussing them with your healthcare provider.

• Hypercholesterolemia: Alternatives may include statins like atorvastatin (Lipitor) and lifestyle changes such as diet modifications and regular exercise.
• Pruritus associated with Partial Biliary Obstruction: Alternatives can include medications like Ursodeoxycholic acid (Actigall, URSO) and antihistamines for itching.
• Diarrhea due to Bile Acid Malabsorption: Dietary changes such as reducing fat intake and medications like loperamide (Imodium) can help.

Recent Updates on Colestipol Research

Recent research has suggested that Colestipol may have potential benefits beyond treating high cholesterol, pruritus, and diarrhea. For instance, a 2022 study found that Colestipol could help in managing chronic idiopathic diarrhea in dogs, suggesting potential applications in veterinary medicine. Always remember to consult with your healthcare provider for the latest updates on any medication. Our telemedicine team stays up-to-date with the latest research to provide you with the best possible care.

Brief Legal Disclaimer

This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.
Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.