Understanding Bismuth Subsalicylate: An Essential Medication Profile

Names of Medication

The medication is commonly known by its US brand name Pepto-Bismol (Bismuth Subsalicylate). The generic name is Bismuth Subsalicylate.

Pharmacologic Category

Bismuth Subsalicylate is part of the pharmacologic category known as Antidiarrheal agents. Other medications in this category include Loperamide (Imodium) and Diphenoxylate/Atropine (Lomotil).

Dosing

Bismuth Subsalicylate is used to treat a variety of conditions in adults. Always consult your healthcare provider before adjusting your medication dosage or schedule.

Diarrhea

For adults with diarrhea, the standard dose of Bismuth Subsalicylate is 2 tablets or 30 mL (525 mg) every half to one hour as needed. Do not exceed 8 doses (4200 mg) in 24 hours.

Upset Stomach, Indigestion, and Heartburn

For these conditions, the dosing is the same as for diarrhea. Adjustments may be necessary based on individual response and tolerability.

Dosage Forms and Strengths

Bismuth Subsalicylate is available in several dosage forms and strengths: chewable tablets (262.4 mg), regular tablets (262.4 mg), and liquid form (262.4 mg per 15 mL and 525 mg per 30 mL).

h2>Administration Instructions

Bismuth Subsalicylate can be taken with or without food. Chewable tablets should be chewed thoroughly before swallowing, while the liquid form should be shaken well before each use. Always follow the dosing instructions on the label or as provided by your healthcare provider.

Adverse Reactions and Side Effects

Like all medications, Bismuth Subsalicylate can cause side effects. However, many people have minimal or no side effects.

Black Stools and Tongue (Common)

One common side effect of Bismuth Subsalicylate is a harmless darkening of the tongue and stool due to the bismuth in the medication. This effect is temporary and will resolve once the medication is stopped.

Allergic Reactions (Rare)

Rarely, Bismuth Subsalicylate can cause serious allergic reactions, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing. If you experience any of these symptoms, seek medical attention immediately.

Contraindications to taking Bismuth Subsalicylate

Contraindications refer to specific situations where a medication should not be used because it may be harmful to the patient. Here are the contraindications for Bismuth Subsalicylate:

Allergy to Salicylates

Individuals who have had an allergic reaction to aspirin or other salicylates should not take Bismuth Subsalicylate. An allergic reaction might include symptoms like hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Reye’s Syndrome

Bismuth Subsalicylate is contraindicated in children and teenagers recovering from viral infections due to the risk of Reye’s syndrome, a rare but serious condition affecting the liver and brain.

Drug to Drug Interactions

It’s crucial to discuss all medications you’re taking with your healthcare provider, as Bismuth Subsalicylate can interact with certain drugs. Some significant interactions include:

Aspirin (Acetylsalicylic Acid)

Since Bismuth Subsalicylate is a type of salicylate, it can interact with aspirin. This interaction could increase the risk of side effects, such as stomach bleeding.

Anticoagulants (Warfarin)

Bismuth Subsalicylate can interfere with the effectiveness of anticoagulants like Warfarin, increasing the risk of bleeding.

Bismuth Subsalicylate in Pregnancy

Bismuth Subsalicylate should be used during pregnancy only if clearly needed and under a healthcare provider’s supervision. Animal studies have not conclusively demonstrated risk, but there are no adequate and well-controlled studies in pregnant women.

Bismuth Subsalicylate while Breastfeeding

It’s unclear whether Bismuth Subsalicylate passes into breast milk. Therefore, it’s best to use this medication while breastfeeding only under the guidance of a healthcare professional.

Estimated Cost of Medication

Without insurance, a 30-day supply of Bismuth Subsalicylate (Pepto-Bismol) costs approximately $15 to $30, depending on the form and dosage. This estimate is based on GoodRx coupon prices but remember, prices can vary depending on the pharmacy, location, and any negotiated agreements between pharmacies and pharmaceutical companies.

Legal Disclaimer

This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.

Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.