US Brand Name: {Altace} ({Ramipril})
Pharmacologic category:
{Angiotensin-converting enzyme (ACE) inhibitors}
Other medications in the same category: {Lisinopril} ({Prinivil}, {Zestril}), {Enalapril} ({Vasotec}), {Captopril} ({Capoten}), {Fosinopril} ({Monopril}), {Quinapril} ({Accupril}), {Perindopril} ({Coversyl}), {Benazepril} ({Lotensin})
Diseases Treated, Dosing, and Treatment Duration:
{Hypertension} (high blood pressure): 2.5-20 mg once daily; adjust dose based on patient response
{Congestive heart failure}: 1.25-10 mg once daily; titrate dose as tolerated
{Myocardial infarction} (heart attack): 2.5-5 mg twice daily; usually continued indefinitely
{Diabetic nephropathy} (kidney disease in people with diabetes): 1.25-10 mg once daily; adjust dose based on patient response
{Chronic kidney disease} (non-diabetic): 1.25-10 mg once daily; adjust dose based on patient response
Post-{myocardial infarction} left ventricular dysfunction: 2.5-5 mg twice daily; usually continued indefinitely
Prevention of cardiovascular events in high-risk patients: 2.5-10 mg once daily; adjust dose based on patient response
{Stroke} prevention: 2.5-10 mg once daily; adjust dose based on patient response
Dosage Forms and Strengths:
Capsules: 1.25 mg, 2.5 mg, 5 mg, and 10 mg
Administration Instructions:
{Ramipril} can be taken with or without food Swallow the capsule whole with a glass of water Take the medication at the same time each day for consistent effects
Adverse Reactions and Side Effects:
{Dizziness} (common): A feeling of lightheadedness or unsteadiness {Headache} (common): Pain or discomfort in the head {Cough} (common): A persistent dry, tickling cough {Hypotension} (less common): Abnormally low blood pressure {Hyperkalemia} (less common): Elevated potassium levels in the blood {Angioedema} (rare): Swelling of the face, lips, or tongue, potentially causing breathing difficulties
Contraindications:
History of {angioedema} related to previous ACE inhibitor treatment Bilateral renal artery stenosis Hypersensitivity to {Ramipril} or any component of the formulation
Drug to Drug Interactions:
{Aliskiren} ({Tekturna}, {Rasilez}): Increased risk of renal impairment, {hypotension}, and {hyperkalemia} {ARBs} (e.g., {Losartan} ({Cozaar}), {Valsartan} ({Diovan})): Increased risk of renal impairment, {hypotension}, and {hyperkalemia} {Potassium-sparing diuretics} (e.g., {Spironolactone} ({Aldactone}), {Triamterene} ({Dyrenium})): Increased risk of {hyperkalemia} {Nonsteroidal anti-inflammatory drugs (NSAIDs)} (e.g., {Ibuprofen} ({Advil}, {Motrin}), {Naproxen} ({Aleve}, {Naprosyn})): Decreased antihypertensive effect, increased risk of renal dysfunction
Pregnancy safety:
{Ramipril} is not considered safe during pregnancy. It can cause injury or death to the fetus when used during the second and third trimesters. If pregnancy is detected, discontinue {Ramipril} as soon as possible.
Breastfeeding safety:
It is not known whether {Ramipril} passes into breast milk. Consult your healthcare provider before breastfeeding while taking {Ramipril}, as the potential risk for the infant should be considered.
Estimated price of a 30-day supply:
The price of {Ramipril} can vary depending on the pharmacy and location. Using a {GoodRx} coupon, a 30-day supply of {Ramipril} 5 mg capsules may cost around $10 to $20. Please note that prices are subject to change and may differ at the time of purchase.
Legal Disclaimer:
This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.