The Kingsley Clinic

Diltiazem (Cardizem) – Uses, Side Effects, and Safety Information

US Brand Name: Cardizem (Diltiazem)

Pharmacologic Category:

Diltiazem belongs to the class of calcium channel blockers. Other medications in the same class include {Amlodipine [Norvasc]}, {Nifedipine [Procardia]}, and {Verapamil [Calan]}.

Diseases Treated, Dosing, and Treatment Duration:

{Hypertension}: The typical dose of Diltiazem for hypertension is 180mg to 240mg once daily. The dose may be adjusted as needed to achieve blood pressure control.
{Angina}: The typical dose of Diltiazem for angina is 120mg to 360mg once daily.
{Coronary artery disease}: The typical dose of Diltiazem for coronary artery disease is 120mg to 480mg once daily.
{Supraventricular tachycardia}: The typical dose of Diltiazem for supraventricular tachycardia is 120mg to 360mg once daily.
{Atrial fibrillation or flutter}: The typical dose of Diltiazem for atrial fibrillation or flutter is 120mg to 360mg once daily.
{Raynaud’s phenomenon}: The typical dose of Diltiazem for Raynaud’s phenomenon is 60mg to 120mg three to four times daily.

Dosage Forms and Strengths:

Tablets: 30mg, 60mg, 90mg, 120mg, 180mg, and 240mg. Extended-release capsules: 60mg, 90mg, 120mg, 180mg, 240mg, 300mg, and 360mg.

Administration Instructions:

It should be taken orally, with or without food. It is important to take Diltiazem at the same time each day to maintain a consistent level of the medication in the blood.

Adverse Reactions and Side Effects:

{Dizziness} (1% to 10%): A feeling of lightheadedness or unsteadiness that may occur with changes in position or movement. {Headache} (1% to 10%): A pain or discomfort in the head. {Edema} (1% to 10%): Swelling of the hands, feet, or ankles. {Flushing} (1% to 10%): A warm and red skin color. {Nausea} (1% to 10%): A feeling of sickness with an inclination to vomit.

Contraindications:

It is contraindicated in patients who are allergic to Diltiazem or any other components of the medication. It should also not be used in patients with certain heart conditions, such as {sick sinus syndrome} or {second- or third-degree AV block}.

Drug to Drug Interactions:

Diltiazem may interact with other medications that affect the heart rate or blood pressure, such as:
{Beta blockers} (e.g. {metoprolol}, {atenolol}) {ACE inhibitors} (e.g. {lisinopril}, {enalapril}) {ARB s} (e.g. {losartan}, {valsartan}) {Diuretics} (e.g. {furosemide}, {hydrochlorothiazide})
These interactions may affect heart rate control or increase the risk of side effects. Patients should inform their healthcare provider of all medications they are taking before starting Diltiazem.

Is this medication safe to take when pregnant?

It may be safe to take during pregnancy, but there is limited information available on the use of Diltiazem during pregnancy. Women who are pregnant should discuss the risks and benefits of taking Diltiazem with their healthcare provider.

Is this medication safe to take when breastfeeding?

It may be safe to take when breastfeeding, but there is limited information available on the use of Diltiazem during breastfeeding. Women who are breastfeeding should discuss the risks and benefits of taking Diltiazem with their healthcare provider.

Estimated Price:

The estimated price of a 30-day supply of Diltiazem ranges from $10 to $20, depending on the dose, the strength, and the pharmacy. Patients may be able to save money on their Diltiazem prescription by using a GoodRx coupon or a similar discount program.

Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.

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