The Kingsley Clinic

Pirbuterol Inhaler: Effective Relief for Asthma and COPD

Summary of Key Points

Pirbuterol is a bronchodilator commonly used to manage respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and other lung-related issues. It works by relaxing the muscles surrounding the airways, making it easier to breathe. Pirbuterol is typically delivered through an inhaler. Always consult your healthcare provider before starting or adjusting your dosage. You can also connect with one of our telemedicine providers for personalized care.

Names of Medication

US Brand Name: Maxair Autohaler

Generic Name: Pirbuterol

The generic name refers to the active ingredient, while the brand name is assigned by the manufacturer. In this article, the generic name will be shown in parentheses.

Pharmacologic Category

Pirbuterol belongs to the Short-Acting Beta-2 Agonist (SABA) category.

Other medications in this category include:

  1. Albuterol
  2. Levalbuterol
  3. Terbutaline

Dosing Information

Pirbuterol is prescribed to treat various respiratory conditions. Below are the recommended doses for adults. Always consult your doctor before making any changes to your dosage. If needed, you can schedule a telemedicine visit with us for further guidance.

Asthma

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As directed by your healthcare provider.

Chronic Obstructive Pulmonary Disease (COPD)

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: Ongoing, as prescribed by your doctor.

Bronchitis

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As directed by your healthcare provider.

Emphysema

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As prescribed by your doctor.

Allergic Rhinitis

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As directed by your healthcare provider.

Exercise-Induced Bronchospasm

Dosage: 2 inhalations (400 mcg total) 15-30 minutes before exercise.

Frequency: Use as needed before exercise.

Length of Treatment: As directed by your healthcare provider.

Respiratory Distress Syndrome

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As prescribed by your doctor.

Cystic Fibrosis

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As directed by your healthcare provider.

Pneumonia

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As prescribed by your doctor.

Pulmonary Edema

Dosage: 1-2 inhalations (200 mcg per inhalation) every 4-6 hours as needed.

Frequency: Up to 12 inhalations per day.

Length of Treatment: As directed by your healthcare provider.

Dosage Forms and Strengths

Inhaler: 200 mcg per inhalation

Administration Instructions

Pirbuterol is administered using an inhaler. To use the inhaler effectively:

  1. Shake the inhaler well before each use.
  2. Exhale fully before placing the mouthpiece in your mouth.
  3. Inhale deeply while pressing down on the inhaler to release the medication.
  4. Hold your breath for 10 seconds, then exhale slowly.
  5. If a second dose is needed, wait at least 1 minute between inhalations.
  6. Rinse your mouth with water after using the inhaler to prevent irritation.

Always follow your healthcare provider’s instructions on how to use your inhaler. If you have any questions or concerns, schedule a telemedicine visit with one of our providers for further assistance.

Contraindications

A contraindication is a specific condition or situation where a medication should not be used because it may cause harm. In the case of Pirbuterol, there are several conditions where it may not be safe. If any of the following apply to you, discuss them with your healthcare provider before starting Pirbuterol.

Allergy to Pirbuterol or similar medications: If you have had an allergic reaction to Pirbuterol or other beta-agonists (such as albuterol or salmeterol), you should not use this medication. Allergic reactions can cause symptoms like rash, swelling, or difficulty breathing, which can be dangerous.

Heart disease: Pirbuterol can increase heart rate and may worsen certain heart conditions, such as arrhythmias (irregular heartbeats) or coronary artery disease. If you have a history of heart disease, your doctor may recommend an alternative treatment.

High blood pressure (hypertension): Since Pirbuterol can raise blood pressure, it may not be suitable for people with uncontrolled hypertension. Your healthcare provider may want to monitor your blood pressure closely or suggest a different medication.

Thyroid disorders: People with hyperthyroidism (an overactive thyroid) may experience increased side effects from Pirbuterol, such as a rapid heart rate or tremors.

Seizure disorders: Pirbuterol can lower the seizure threshold, meaning it may increase the risk of seizures in people with epilepsy or other seizure disorders.

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Drug to Drug Interactions

Several medications can interact with Pirbuterol, potentially reducing its effectiveness or increasing the risk of side effects. If you are taking any of the following medications, inform your healthcare provider:

  1. Beta-blockers (e.g., propranolol, metoprolol): These medications, commonly prescribed for high blood pressure or heart conditions, can counteract Pirbuterol’s effects, making it less effective.
  2. Diuretics (e.g., furosemide, hydrochlorothiazide): Often used to manage high blood pressure or fluid retention, these drugs can increase the risk of low potassium levels when combined with Pirbuterol, which may lead to muscle cramps or heart complications.
  3. MAO inhibitors (e.g., phenelzine, tranylcypromine): These antidepressants can raise the risk of serious side effects, such as dangerously high blood pressure, when taken with Pirbuterol.
  4. Tricyclic antidepressants (e.g., amitriptyline, nortriptyline): These medications may also increase the likelihood of cardiovascular side effects when used alongside Pirbuterol.

Pirbuterol in Pregnancy

Is it safe to take Pirbuterol during pregnancy?

There is limited information on the safety of Pirbuterol during pregnancy. While animal studies have not demonstrated significant harm to the fetus, there is not enough research in humans to confirm its safety. If you are pregnant or planning to become pregnant, it’s important to discuss the potential risks and benefits of using Pirbuterol with your healthcare provider. They will help you weigh the risks of untreated respiratory conditions against any potential risks to your baby.

Pirbuterol while Breastfeeding

Is it safe to take Pirbuterol while breastfeeding?

The safety of Pirbuterol during breastfeeding is not well established. It is unclear whether Pirbuterol passes into breast milk or what effects it might have on a nursing infant. If you are breastfeeding, consult your healthcare provider to determine whether the benefits of using Pirbuterol outweigh any potential risks. Your provider may recommend monitoring your baby for any signs of side effects, such as irritability or feeding difficulties.

Estimated Cost of Pirbuterol

The cost of a 30-day supply of Pirbuterol without insurance can vary. With a GoodRX coupon, the price typically ranges from $40 to $80, depending on the pharmacy and location. Prices may fluctuate, so it’s always a good idea to check for updated discounts or speak with your pharmacist.

Possible Alternatives to Pirbuterol

If Pirbuterol is not the right option for you, several alternative treatments and lifestyle changes may help manage your respiratory condition. Always discuss these alternatives with your healthcare provider before making any changes to your treatment plan. Our telemedicine providers are available to help you explore these options.

  1. Asthma: Alternatives include inhaled corticosteroids (e.g., fluticasone), long-acting beta-agonists (e.g., salmeterol), or leukotriene modifiers (e.g., montelukast). Lifestyle changes, such as avoiding triggers (e.g., allergens, smoke) and engaging in regular exercise, can also help manage asthma symptoms.
  2. Chronic Obstructive Pulmonary Disease (COPD): Long-acting bronchodilators (e.g., tiotropium) and inhaled corticosteroids may be used as alternatives. Quitting smoking and participating in pulmonary rehabilitation are essential lifestyle changes for managing COPD.
  3. Bronchitis: Inhaled bronchodilators, such as albuterol, may help relieve symptoms. Staying hydrated and avoiding irritants like smoke can also be beneficial.
  4. Emphysema: Long-acting bronchodilators and oxygen therapy may be considered alternatives. Quitting smoking and engaging in pulmonary rehabilitation can significantly improve quality of life.
  5. Allergic Rhinitis: Antihistamines (e.g., loratadine) or nasal corticosteroids (e.g., fluticasone) may be used. Avoiding allergens and using air purifiers can help reduce symptoms.
  6. Exercise-Induced Bronchospasm: Short-acting beta-agonists (e.g., albuterol) taken before exercise may help. Warming up before physical activity and avoiding cold, dry air can also reduce symptoms.
  7. Respiratory Distress Syndrome: Treatment typically involves oxygen therapy and mechanical ventilation. Discuss specific treatment options with your healthcare provider.
  8. Cystic Fibrosis: Inhaled medications (e.g., dornase alfa) and chest physiotherapy may be alternatives. Maintaining a healthy diet and staying active can also help manage symptoms.
  9. Pneumonia: Antibiotics are the primary treatment for bacterial pneumonia. Staying hydrated and getting plenty of rest are important for recovery.
  10. Pulmonary Edema: Diuretics (e.g., furosemide) and oxygen therapy are commonly used. Managing underlying conditions, such as heart disease, is crucial for preventing future episodes.

Recent Updates on Pirbuterol Research

Recent studies on Pirbuterol have focused on its effectiveness compared to other short-acting beta-agonists, such as albuterol. While Pirbuterol is effective in relieving bronchospasm, newer inhalers with more advanced delivery systems may offer improved convenience and efficacy. Ongoing research is also exploring the long-term safety of Pirbuterol in patients with chronic respiratory conditions. As with any medication, it is important to stay informed about the latest research and discuss any concerns with your healthcare provider. Our telemedicine providers are available to help you stay up-to-date on the latest treatment options.

James Kingsley
James Kingsley

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