Meclizine: Uses, Dosage & Side Effects for Motion Sickness & Vertigo

Summary of Key Points

Meclizine is a medication frequently used to manage motion sickness, vertigo, and other inner ear disorders. It helps relieve symptoms such as nausea, vomiting, and dizziness. Meclizine is available in both prescription and over-the-counter forms. Always follow your healthcare provider’s instructions and consult a doctor before making any changes to your dosage. You can also connect with one of our telemedicine providers for personalized care.

Names of Medication

US Brand Name: Antivert (Meclizine)

US Brand Name: Bonine (Meclizine)

US Brand Name: Dramamine Less Drowsy (Meclizine)

The term ‘generic name’ refers to the active ingredient in the medication, which remains consistent across different brands. In this case, Meclizine is the generic name, listed in parentheses.

Pharmacologic Category

Antihistamines (H1 receptor antagonists)

Antiemetics

Meclizine Dosage

Meclizine is used to treat various conditions related to dizziness, nausea, and balance disorders. Below are the recommended doses for adults. Always consult your doctor before adjusting your dose, or connect with one of our telemedicine providers for guidance.

Meclizine for Motion Sickness

Dosage: 25-50 mg taken 1 hour before travel.

Frequency: May be repeated every 24 hours if needed.

Length of Treatment: Use as needed during travel.

Meclizine for Vertigo and Dizziness

Dosage: 25-100 mg per day, divided into smaller doses.

Frequency: Taken 1-4 times daily, depending on severity.

Length of Treatment: As directed by your healthcare provider.

Meclizine for Meniere’s Disease

Dosage: 25-100 mg per day, divided into smaller doses.

Frequency: Taken 1-4 times daily, depending on symptoms.

Length of Treatment: As directed by your healthcare provider.

Meclizine for Nausea and Vomiting (Related to Inner Ear Disorders)

Dosage: 25-50 mg as needed.

Frequency: Every 24 hours as needed.

Length of Treatment: Use as directed by your healthcare provider.

Meclizine for Seasickness and Air Sickness

Dosage: 25-50 mg taken 1 hour before travel.

Frequency: May be repeated every 24 hours if needed.

Length of Treatment: Use as needed during travel.

Dosage Forms and Strengths

Tablets: 12.5 mg, 25 mg, 50 mg

Chewable Tablets: 25 mg

Administration Instructions for Meclizine

Meclizine is typically taken orally, with or without food. If using the chewable tablet, make sure to chew it thoroughly before swallowing. For motion sickness, take the medication about 1 hour before travel to prevent symptoms. Follow your healthcare provider’s instructions carefully, and do not exceed the prescribed dose. If you have any questions about how to take Meclizine, consult one of our telemedicine providers for guidance.

Meclizine Side Effects and Adverse Reactions

Like all medications, Meclizine can cause side effects. Most are mild, but some may be more serious. If you experience severe side effects, contact your healthcare provider immediately.

1. Drowsiness (Common): Meclizine may cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
2. Dry Mouth (Common): You may experience dry mouth while taking Meclizine. Drinking water or chewing gum can help alleviate this symptom.
3. Blurred Vision (Less Common): Some patients may experience blurred vision. If this occurs, consult your healthcare provider.
4. Headache (Less Common): Headaches can occur as a side effect. If persistent, contact your doctor.
5. Allergic Reactions (Rare): In rare cases, Meclizine can cause allergic reactions, such as rash, itching, or swelling. Seek medical attention immediately if you experience any of these symptoms.

Contraindications for Meclizine

A contraindication is a specific situation or condition where a medication should not be used because it may cause harm. For Meclizine, certain conditions make it unsafe or inappropriate to take. Below is a list of contraindications for Meclizine, along with explanations for why it is not recommended in these cases:

1. Hypersensitivity or allergy to Meclizine: If you have had an allergic reaction to Meclizine or any of its ingredients, taking it again could cause serious allergic reactions, such as rash, swelling, or difficulty breathing.
2. Severe liver disease: Meclizine is processed by the liver, and if you have severe liver disease, your body may not break down the medication properly, leading to potential toxicity.
3. Glaucoma: Meclizine has anticholinergic effects, which can increase pressure in the eyes. This can worsen glaucoma, a condition that already involves increased eye pressure.
4. Enlarged prostate (Benign Prostatic Hyperplasia): Meclizine’s anticholinergic properties can worsen urinary retention, a common issue in men with an enlarged prostate.
5. Asthma or other respiratory conditions: Meclizine can thicken mucus and make it harder to clear your airways, which can worsen breathing problems in people with asthma or chronic obstructive pulmonary disease (COPD).

Meclizine Drug Interactions

Meclizine can interact with other medications, potentially increasing side effects or altering how the medications work. Below are some common drugs that may interact with Meclizine:

1. Alcohol: Combining alcohol with Meclizine can increase drowsiness and dizziness, making it dangerous to drive or operate machinery.
2. Central nervous system (CNS) depressants: Medications like benzodiazepines (e.g., Xanax [alprazolam], Valium [diazepam]) or opioids (e.g., OxyContin [oxycodone], Vicodin [hydrocodone]) can increase the sedative effects of Meclizine, leading to excessive drowsiness or respiratory depression.
3. Anticholinergic drugs: Medications like Benadryl (diphenhydramine) or Atrovent (ipratropium) can increase the risk of side effects such as dry mouth, constipation, or difficulty urinating when taken with Meclizine.
4. Tricyclic antidepressants: Drugs like Elavil (amitriptyline) or Pamelor (nortriptyline) can enhance the anticholinergic effects of Meclizine, leading to increased drowsiness, confusion, or difficulty with urination.

Meclizine in Pregnancy

Is It Safe to Take Meclizine When Pregnant?

Meclizine is classified as a Category B medication by the FDA. This means that while animal studies have not shown harm to the fetus, there are not enough well-controlled studies in pregnant women to confirm its safety. Meclizine is sometimes prescribed to manage nausea and vomiting during pregnancy, particularly for motion sickness. However, it’s crucial to consult your healthcare provider before taking it. They will carefully weigh the potential benefits and risks to ensure it’s safe for both you and your baby.

Meclizine While Breastfeeding

Is It Safe to Take Meclizine While Breastfeeding?

There is limited information available regarding the safety of Meclizine during breastfeeding. The medication may pass into breast milk in small amounts, which could potentially cause drowsiness or irritability in a nursing infant. It’s important to speak with your healthcare provider before using Meclizine while breastfeeding to determine if it’s the best option for you and your baby.

Estimated Cost of Meclizine

The cost of a 30-day supply of Meclizine without insurance can vary depending on the pharmacy and location. However, with a GoodRx coupon, the estimated price for a 30-day supply of Meclizine 25 mg typically ranges from $8 to $15. Prices may fluctuate, so it’s a good idea to check with your local pharmacy or use a discount service like GoodRx to find the most affordable option.

Possible Alternatives to Meclizine

If you’re exploring alternatives to Meclizine for any of the following conditions, it’s essential to discuss these options with your healthcare provider. You can also schedule a telemedicine appointment with one of our providers to explore these alternatives further.

1. Motion sickness: Alternatives include non-drowsy antihistamines like Bonine (cyclizine) or scopolamine patches. Lifestyle adjustments, such as avoiding large meals before travel, focusing on the horizon, and using acupressure bands, may also provide relief.
2. Vertigo: Physical therapy exercises, such as the Epley maneuver, can help reposition crystals in the inner ear that cause vertigo. Medications like Valium (diazepam) or Antivert (meclizine) may also be prescribed.
3. Dizziness: Staying hydrated, avoiding sudden movements, and addressing underlying causes like low blood pressure or anxiety can help manage dizziness. Medications such as Antivert (meclizine) or Valium (diazepam) may also be considered.
4. Meniere’s disease: Common treatments include a low-sodium diet, diuretics, and vestibular rehabilitation therapy. In some cases, surgery may be recommended.
5. Nausea and vomiting: Ginger supplements or acupressure wristbands can help with mild nausea. For more severe cases, prescription medications like Zofran (ondansetron) or Phenergan (promethazine) may be used.
6. Inner ear disorders: Vestibular rehabilitation therapy and medications like Antivert (meclizine) or Valium (diazepam) may help manage symptoms.
7. Vestibular disorders: Physical therapy, balance exercises, and medications such as Antivert (meclizine) or Valium (diazepam) may be used to treat vestibular disorders.
8. Seasickness or air sickness: Non-drowsy antihistamines like Bonine (cyclizine) or scopolamine patches may be effective. Lifestyle changes, such as focusing on the horizon and staying hydrated, can also help.

Recent Updates on Meclizine Research

Recent studies have explored the potential use of Meclizine beyond its traditional role in treating motion sickness and vertigo. Some research has focused on its neuroprotective effects, particularly in conditions like Parkinson’s disease and Alzheimer’s disease, due to its ability to inhibit mitochondrial dysfunction. However, these studies are still in the early stages, and more research is needed to determine whether Meclizine could be a viable treatment for these conditions.

Additionally, ongoing studies are investigating the long-term safety of Meclizine, particularly in older adults. The drug’s anticholinergic effects may increase the risk of cognitive decline in this population. If you’re concerned about the long-term use of Meclizine, especially if you’re older, it’s important to discuss this with your healthcare provider. You can also schedule a telemedicine appointment with one of our providers to review your treatment plan.

James Kingsley

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