Celiprolol: Uses, Dosage, Side Effects, and Interactions Guide

Summary of Key Points

Celiprolol is a beta-blocker used to manage conditions such as high blood pressure (hypertension), chest pain (angina), and heart rhythm disorders. It works by lowering blood pressure and reducing the heart’s workload. Patients prescribed Celiprolol should carefully follow their healthcare provider’s instructions. Common side effects may include dizziness, fatigue, and cold extremities. Always consult your doctor before making any changes to your medication regimen.

Names of Medication

US Brand Name: Celiprolol

Generic Name: Celiprolol

The generic name refers to the active ingredient in the medication, which remains consistent across all brands containing this ingredient.

Pharmacologic Category

Beta-blocker, Beta-1 selective

Other medications in this category include Atenolol, Metoprolol, and Bisoprolol.

Celiprolol Dosage and Uses

Celiprolol is prescribed for various conditions, with the dosage and frequency tailored to the specific condition being treated. Always adhere to your healthcare provider’s instructions and consult them before adjusting your dose. You can also schedule a telemedicine appointment with one of our providers for personalized guidance.

Celiprolol for Hypertension (High Blood Pressure)

The typical starting dose is 200 mg once daily. Your doctor may increase the dose to 400 mg daily depending on how well your blood pressure responds to the medication.

Celiprolol for Angina Pectoris (Chest Pain)

The usual dose is 200 mg once daily. In some cases, your doctor may increase the dose to 400 mg daily to better manage your symptoms.

Celiprolol for Heart Failure

The typical dose is 200 mg once daily, but your doctor will monitor your condition closely and adjust the dose as needed.

Celiprolol for Atrial Fibrillation (Irregular Heartbeat)

The starting dose is 200 mg once daily. Your doctor may adjust the dose based on your response to the treatment.

Celiprolol for Tachycardia (Fast Heart Rate)

The usual dose is 200 mg once daily, with adjustments made by your healthcare provider as necessary.

Celiprolol for Myocardial Infarction (Heart Attack)

The typical starting dose is 200 mg once daily. Your doctor may adjust the dose depending on your recovery and overall health.

Celiprolol for Arrhythmia (Irregular Heartbeat)

The dose is usually 200 mg once daily, but your doctor may modify it based on your individual response to the medication.

Celiprolol for Coronary Artery Disease

The recommended dose is 200 mg once daily, with possible adjustments made by your healthcare provider.

Celiprolol for Peripheral Vascular Disease

The usual dose is 200 mg once daily. Your doctor may adjust the dose depending on the severity of your condition.

Celiprolol for Anxiety Disorders

The typical dose is 200 mg once daily. Your doctor may adjust the dose based on your symptoms and how well you respond to the treatment.

Dosage Forms and Strengths

Tablets: 200 mg, 400 mg

Administration Instructions for Celiprolol

Celiprolol should be taken orally, typically once daily, with or without food. It is important to take the medication at the same time each day to maintain consistent levels in your body. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Never double up on doses.

Celiprolol Side Effects and Adverse Reactions

Like all medications, Celiprolol may cause side effects. Some are more common, while others are rare. If you experience any severe or persistent side effects, contact your healthcare provider immediately or schedule a telemedicine appointment with us.

Common Celiprolol Side Effects

1. Dizziness: Feeling lightheaded, especially when standing up quickly.
2. Fatigue: Feeling unusually tired or weak.
3. Cold Extremities: Hands and feet may feel cold due to reduced blood flow.

Less Common Celiprolol Side Effects

1. Shortness of Breath: Difficulty breathing, especially during physical activity.
2. Bradycardia: A slower-than-normal heart rate.
3. Depression: Feeling unusually sad or hopeless.

Rare Celiprolol Side Effects

1. Allergic Reactions: Rash, itching, swelling, or difficulty breathing.
2. Heart Failure Worsening: Symptoms such as swelling in the legs, difficulty breathing, or sudden weight gain.

Contraindications for Celiprolol

A contraindication is a specific condition where a medication should not be used because it may cause harm. It’s important to know if any of these apply to you before starting Celiprolol.

Celiprolol is contraindicated in the following situations:

1. Severe bradycardia (slow heart rate): Celiprolol can further reduce the heart rate, leading to dangerously low levels in patients with an already slow heartbeat.
2. Heart block: If you have certain types of heart block (a condition where the heart’s electrical signals are delayed or blocked), Celiprolol can worsen this and lead to serious complications.
3. Uncontrolled heart failure: Celiprolol can reduce the heart’s ability to pump blood effectively, potentially worsening heart failure if not well-managed.
4. Asthma or severe chronic obstructive pulmonary disease (COPD): Celiprolol can narrow the airways, which may trigger breathing difficulties in patients with these respiratory conditions.
5. Severe peripheral artery disease: Celiprolol can reduce blood flow to the extremities, worsening symptoms in patients with poor circulation.
6. Allergy to Celiprolol or any of its components: If you have a known allergy to Celiprolol, you should not take this medication as it could trigger an allergic reaction.

Drug to Drug Interactions

Celiprolol, a beta-blocker, can interact with other medications, potentially diminishing its effectiveness or increasing the likelihood of side effects. It’s essential to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements, to prevent harmful interactions.

Medications that may interact with Celiprolol include:

1. Calcium channel blockers (e.g., Verapamil, Diltiazem): These medications lower heart rate and blood pressure. When combined with Celiprolol, they may cause an excessive drop in heart rate or blood pressure.
2. Clonidine (Catapres): Taking Clonidine with Celiprolol can lead to a dangerous spike in blood pressure if Clonidine is stopped abruptly.
3. Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., Ibuprofen, Naproxen): NSAIDs can reduce the blood pressure-lowering effects of Celiprolol.
4. Antiarrhythmic drugs (e.g., Amiodarone, Flecainide): These medications increase the risk of heart rhythm disturbances when taken with Celiprolol.
5. Insulin or oral diabetes medications (e.g., Metformin, Glipizide): Celiprolol may mask symptoms of low blood sugar, making it harder to recognize hypoglycemia.

Celiprolol in Pregnancy

Is it safe to take Celiprolol during pregnancy?

Celiprolol is generally not recommended during pregnancy unless the benefits clearly outweigh the risks. Beta-blockers like Celiprolol can affect fetal growth and may lead to complications such as low birth weight or a slow heart rate in the newborn. If you are pregnant or planning to become pregnant, it’s important to discuss this with your healthcare provider. They can help you evaluate the risks and benefits and determine whether Celiprolol is the best option for you.

Celiprolol while Breastfeeding

Is it safe to take Celiprolol while breastfeeding?

Celiprolol may pass into breast milk in small amounts. While the potential risk to a nursing infant is not fully understood, it is generally advised to avoid beta-blockers like Celiprolol while breastfeeding unless absolutely necessary. If you are breastfeeding, consult your healthcare provider to discuss the potential risks and whether an alternative medication might be more suitable.

Estimated Cost of Celiprolol

The estimated cost of a 30-day supply of Celiprolol without insurance, using a GoodRX coupon, ranges from $20 to $50 depending on the pharmacy and dosage. Prices may vary, so it’s a good idea to check with your local pharmacy or use a discount service like GoodRX to find the best price.

Possible Alternatives to Celiprolol

If Celiprolol is not appropriate for you, there are alternative treatments and lifestyle changes that may help manage your condition. Always consult your healthcare provider before making any changes to your treatment plan. You can also schedule a telemedicine appointment with one of our providers to discuss these options in detail.

1. Hypertension (High Blood Pressure): Alternatives include other beta-blockers like Metoprolol, or lifestyle changes such as reducing salt intake, regular exercise, and weight management.
2. Angina Pectoris: Calcium channel blockers (e.g., Amlodipine) or nitrates (e.g., Nitroglycerin) may be considered as alternatives. Lifestyle changes like quitting smoking and managing stress can also help.
3. Heart Failure: ACE inhibitors (e.g., Lisinopril) or ARBs (e.g., Losartan) may be used. Lifestyle changes such as reducing sodium intake and monitoring fluid levels can also be beneficial.
4. Atrial Fibrillation: Anticoagulants (e.g., Warfarin) or other rate-controlling medications like Diltiazem may be considered.
5. Tachycardia: Calcium channel blockers or antiarrhythmic drugs may be used as alternatives. Reducing caffeine and alcohol intake can also help manage symptoms.
6. Myocardial Infarction (Heart Attack): ACE inhibitors, statins, and lifestyle changes such as quitting smoking and adopting a heart-healthy diet are often recommended.
7. Arrhythmia: Antiarrhythmic drugs or procedures like catheter ablation may be considered. Avoiding stimulants like caffeine can also help.
8. Coronary Artery Disease: Statins (e.g., Atorvastatin) and lifestyle changes such as regular exercise and a heart-healthy diet can be effective.
9. Peripheral Vascular Disease: Antiplatelet medications (e.g., Aspirin) and lifestyle changes such as quitting smoking and increasing physical activity may help improve symptoms.
10. Anxiety Disorders: Medications like SSRIs (e.g., Sertraline) or therapy such as cognitive-behavioral therapy (CBT) may be considered as alternatives.

Recent Updates on Celiprolol Research

Recent studies have explored the potential benefits of Celiprolol in patients with vascular connective tissue disorders, such as Ehlers-Danlos syndrome. Some research suggests that Celiprolol may help reduce the risk of arterial rupture in these patients, though further studies are needed to confirm these findings. Additionally, ongoing research is investigating the use of Celiprolol in preventing cardiovascular events in high-risk populations. As always, it’s important to consult your healthcare provider to discuss the latest research and how it may apply to your treatment plan.

James Kingsley

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