Capsaicin Benefits: Effective Pain Relief & Topical Uses Explained

Capsaicin: Key Points and Benefits

Capsaicin is a topical medication commonly used to alleviate pain associated with conditions such as arthritis, neuropathy, and muscle discomfort. It works by decreasing the amount of a chemical in the body that transmits pain signals to the brain. Capsaicin is available in various forms, including creams, gels, and patches. It’s important to consult a healthcare provider before starting or adjusting your dose. Our telemedicine providers are also available to assist you with any questions or concerns.

Capsaicin Medication Names

Zostrix (Capsaicin)

Capzasin-HP (Capsaicin)

Salonpas-Hot (Capsaicin)

The generic name, listed in parentheses, is the active ingredient in all these brands.

Pharmacologic Category of Capsaicin

Topical Analgesic

Counterirritant

Capsaicin Dosing Guidelines

Capsaicin is used to treat a variety of conditions in adults. Below are the recommended doses for each condition. Always consult your doctor before making any changes to your treatment plan. Our telemedicine providers are available to help you manage your care.

Capsaicin for Neuropathic Pain

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected area 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: It may take 2-4 weeks to experience the full effect.

Capsaicin for Osteoarthritis

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected joints 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: Use for at least 2 weeks to evaluate effectiveness.

Capsaicin for Rheumatoid Arthritis

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected joints 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: Use for at least 2 weeks to assess effectiveness.

Capsaicin for Postherpetic Neuralgia (Pain After Shingles)

Dosage: Apply a high-dose patch (8%) to the affected area for 60 minutes under medical supervision.

Frequency: Every 3 months as needed.

Length of Treatment: Single application, with the option to repeat every 3 months if necessary.

Capsaicin for Diabetic Neuropathy

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected area 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: It may take 2-4 weeks to achieve the full effect.

Capsaicin for Psoriasis

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected area 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: Use for at least 2 weeks to determine effectiveness.

Capsaicin for Fibromyalgia

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected area 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: Use for at least 2 weeks to assess effectiveness.

Capsaicin for Muscle Pain

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the affected area 3 to 4 times daily.

Frequency: 3-4 times a day.

Length of Treatment: Use for at least 2 weeks to evaluate effectiveness.

Capsaicin for Shingles

Dosage: Apply a high-dose patch (8%) to the affected area for 60 minutes under medical supervision.

Frequency: Every 3 months as needed.

Length of Treatment: Single application, with the option to repeat every 3 months if necessary.

Capsaicin for Cluster Headaches

Dosage: Apply a thin layer of cream (0.025% to 0.075%) to the nostrils under medical supervision.

Frequency: As directed by your healthcare provider.

Length of Treatment: Use as needed, based on medical advice.

Capsaicin Dosage Forms and Strengths

Cream: 0.025%, 0.075%

Gel: 0.025%, 0.075%

Patch: 8%

Lotion: 0.025%

Capsaicin Contraindications

A contraindication is a specific situation where a treatment or medication should not be used because it may cause harm. There are several instances where Capsaicin is not recommended.

Allergy to Capsaicin or its components: If you have a known allergy to Capsaicin or any of its ingredients, using it could trigger an allergic reaction, which may include rash, itching, swelling, or difficulty breathing.

Broken or irritated skin: Capsaicin is applied topically, and if you have open wounds or irritated skin, it can cause severe burning and discomfort. It may also delay the healing process.

Severe hypertension (high blood pressure): Capsaicin can cause a temporary increase in blood pressure in some individuals. If you have uncontrolled high blood pressure, using Capsaicin may exacerbate your condition.

History of heart disease: Capsaicin can sometimes cause a burning sensation or discomfort that may resemble heart-related symptoms. If you have a history of heart disease, this could lead to unnecessary anxiety or confusion about your symptoms.

Capsaicin Drug Interactions

Capsaicin can interact with certain medications. It’s important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, supplements, and herbal products. The following medications may interact with Capsaicin:

Blood pressure medications: Capsaicin may interact with medications used to lower blood pressure, such as Lisinopril (Zestril) or Amlodipine (Norvasc), potentially causing fluctuations in blood pressure.

Anticoagulants (blood thinners): Capsaicin may increase the risk of bleeding when used with blood-thinning medications like Warfarin (Coumadin) or Clopidogrel (Plavix).

ACE inhibitors: Capsaicin may enhance the cough reflex, a common side effect of ACE inhibitors such as Enalapril (Vasotec) or Ramipril (Altace).

Topical anesthetics: Using Capsaicin with other topical medications like Lidocaine (Lidoderm) may reduce the effectiveness of either medication or increase skin irritation.

Capsaicin in Pregnancy

Is it safe to use Capsaicin during pregnancy?

Research on the safety of Capsaicin use during pregnancy is limited. Although it is applied topically and only minimally absorbed into the bloodstream, it’s important to exercise caution. If you are pregnant or planning to become pregnant, it’s best to consult your healthcare provider before using Capsaicin. Our telemedicine providers are also available to discuss your options and help you make an informed decision.

Capsaicin While Breastfeeding

Is it safe to use Capsaicin while breastfeeding?

There is not enough data to definitively confirm the safety of Capsaicin use while breastfeeding. Since it is applied to the skin, the likelihood of it passing into breast milk is low. However, it’s important to avoid applying it to areas where your baby might come into contact, such as your chest. Always consult your healthcare provider before using Capsaicin while breastfeeding. You can also schedule a telemedicine appointment with one of our providers to discuss your specific situation.

Estimated Cost of Capsaicin Cream

The cost of a 30-day supply of Capsaicin cream can vary depending on the brand and strength. With a GoodRX coupon, the estimated price for over-the-counter Capsaicin cream (0.025% or 0.075%) typically ranges from $10 to $20. Prices may differ based on your location and pharmacy, so it’s a good idea to check for discounts or coupons before making a purchase.

Possible Alternatives to Capsaicin

If Capsaicin is not suitable for you, there are other treatments and lifestyle changes that may help manage your condition. Always discuss these alternatives with your healthcare provider before making any changes to your treatment plan. Our telemedicine providers are available to help you explore these options.

Neuropathic Pain

Alternatives include medications such as Gabapentin (Neurontin) or Pregabalin (Lyrica). Lifestyle modifications, including regular exercise and physical therapy, may also help alleviate symptoms.

Osteoarthritis

Nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen (Advil) or Naproxen (Aleve) are commonly used. Weight management and low-impact exercises, such as swimming, can also help reduce joint pain.

Rheumatoid Arthritis

Disease-modifying antirheumatic drugs (DMARDs) like Methotrexate (Trexall) or biologics such as Adalimumab (Humira) may be prescribed. Physical therapy and dietary adjustments can also be beneficial.

Postherpetic Neuralgia

Common alternatives include anticonvulsants like Gabapentin (Neurontin) or antidepressants such as Amitriptyline (Elavil). Nerve blocks or transcutaneous electrical nerve stimulation (TENS) may also provide relief.

Diabetic Neuropathy

Medications like Duloxetine (Cymbalta) or Pregabalin (Lyrica) are often prescribed. Managing blood sugar levels through diet and exercise is crucial to prevent further nerve damage.

Psoriasis

Topical treatments such as corticosteroids or vitamin D analogs, as well as biologic therapies like Secukinumab (Cosentyx), may be effective alternatives. Stress management and keeping the skin well-moisturized can also help manage symptoms.

Fibromyalgia

Antidepressants like Amitriptyline (Elavil) or Duloxetine (Cymbalta) are commonly used treatments. Non-drug alternatives include regular exercise, stress reduction techniques, and cognitive behavioral therapy (CBT).

Muscle Pain

NSAIDs such as Ibuprofen (Advil) or muscle relaxants like Cyclobenzaprine (Flexeril) may be helpful. Stretching, massage, and heat therapy can also provide relief from muscle pain.

Shingles

Antiviral medications like Valacyclovir (Valtrex) or Acyclovir (Zovirax) are often prescribed. Keeping the affected area clean and applying cool compresses can help manage symptoms.

Cluster Headaches

Oxygen therapy and medications such as Sumatriptan (Imitrex) are common treatments. Avoiding known triggers, such as alcohol or strong odors, may help reduce the frequency of attacks.

Recent Updates on Capsaicin Research

Recent studies have explored Capsaicin’s potential beyond pain management. For instance, research is ongoing into its role in weight loss, as Capsaicin may help boost metabolism and fat oxidation. Additionally, some studies are investigating its potential in cancer treatment, as Capsaicin has been shown to induce apoptosis (cell death) in certain cancer cells in laboratory settings. However, these studies are still in the early stages, and more research is needed before Capsaicin can be recommended for these purposes.

As always, consult your healthcare provider before making any changes to your treatment plan. If you have questions about Capsaicin or want to explore whether it’s right for you, our telemedicine providers are available to assist you.

James Kingsley

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