Acebutolol Medication: Uses, Dosage, Side Effects & Interactions

Summary of Key Points

Acebutolol is a beta-blocker commonly prescribed to manage high blood pressure (hypertension), chest pain (angina), and irregular heartbeats (arrhythmias). It works by slowing the heart rate and reducing the heart’s workload, which can help prevent heart attacks and improve overall heart function. Always consult your healthcare provider before making any changes to your medication. Our telemedicine providers are available to assist you in managing your treatment plan.

Names of Medication

US Brand Name: Sectral

Generic Name: Acebutolol

The generic name refers to the active ingredient in the medication, while the brand name is assigned by the manufacturer. In this case, Acebutolol is the generic name.

Pharmacologic Category

Acebutolol belongs to a class of medications known as beta-blockers. Other medications in this category include:

1. Atenolol
2. Metoprolol
3. Propranolol
4. Bisoprolol

Acebutolol Dosage

Acebutolol is prescribed for various conditions, and the dosage will depend on the specific condition being treated. Always follow your doctor’s instructions and consult one of our telemedicine providers before making any adjustments to your dose.

Hypertension (High Blood Pressure)

Initial dose: 400 mg per day, either as a single dose or divided into two doses.

Maintenance dose: 400-800 mg per day, depending on your response to the medication.

Angina (Chest Pain)

Initial dose: 400 mg per day, either as a single dose or divided into two doses.

Maintenance dose: 600-1200 mg per day, depending on your response.

Arrhythmias (Irregular Heartbeat)

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Heart Failure

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Myocardial Infarction (Heart Attack)

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Tachycardia (Fast Heart Rate)

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Atrial Fibrillation

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Anxiety

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Migraine Prevention

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Hyperthyroidism (Overactive Thyroid)

Initial dose: 200 mg twice daily.

Maintenance dose: Adjust based on response, up to 1200 mg per day.

Dosage Forms and Strengths

Capsules: 200 mg, 400 mg

Administration Instructions for Acebutolol

Acebutolol should be taken orally, with or without food. It is important to take this medication at the same time each day to maintain consistent levels in your bloodstream. Do not stop taking Acebutolol suddenly, as this can lead to serious heart complications. If you miss a dose, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose. Never double up on doses. Always follow your healthcare provider’s instructions, and if you have any questions, consult one of our telemedicine providers.

Adverse Reactions and Side Effects of Acebutolol

Like all medications, Acebutolol may cause side effects. Some are more common, while others are rare but potentially serious. If you experience any side effects, contact your healthcare provider promptly.

Common Side Effects

1. Fatigue: Feeling unusually tired or weak.
2. Dizziness: Feeling lightheaded, especially when standing up quickly.
3. Headache: Mild to moderate headaches.
4. Slow heart rate: Your heart may beat slower than usual.

Less Common but Serious Side Effects

1. Shortness of breath: Difficulty breathing or feeling like you can’t catch your breath.
2. Swelling: Swelling in the hands, feet, or ankles.
3. Chest pain: New or worsening chest pain.
4. Severe allergic reactions: Rash, itching, swelling, or trouble breathing.

Contraindications for Acebutolol

A contraindication is a specific condition or situation where a medication should not be used because it may cause harm. If you have any of the following conditions, taking Acebutolol may not be safe for you.

1. Severe bradycardia (slow heart rate): Acebutolol can further slow your heart rate, which could be dangerous if your heartbeat is already very slow.
2. Heart block (second or third degree): This is a condition where the electrical signals in your heart are delayed or blocked. Acebutolol can worsen this condition, leading to more severe heart problems.
3. Cardiogenic shock: A life-threatening condition where the heart suddenly can’t pump enough blood to meet the body’s needs. Acebutolol can reduce heart function, worsening this condition.
4. Uncontrolled heart failure: If your heart failure is not well-managed, Acebutolol can further decrease heart function, worsening symptoms.
5. Severe asthma or chronic obstructive pulmonary disease (COPD): Acebutolol can constrict airways, making breathing more difficult for people with these conditions.
6. Hypersensitivity to Acebutolol or beta-blockers: If you have had an allergic reaction to Acebutolol or other beta-blockers, avoid this medication to prevent a serious allergic reaction.

Drug to Drug Interactions

Acebutolol can interact with other medications, which may increase the risk of side effects or reduce the effectiveness of your treatment. It’s important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements. Some key drug interactions include:

Calcium channel blockers (e.g., Verapamil, Diltiazem): These medications lower heart rate and blood pressure. When taken with Acebutolol, their effects may be amplified, potentially leading to dangerously low heart rates or blood pressure.

Antiarrhythmic drugs (e.g., Amiodarone, Quinidine): These medications are used to treat irregular heartbeats. Combining them with Acebutolol can increase the risk of heart rhythm disturbances.

Clonidine (brand name: Catapres): Both Clonidine and Acebutolol lower blood pressure. If Clonidine is stopped suddenly while taking Acebutolol, it can cause a dangerous spike in blood pressure.

Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., Ibuprofen, Naproxen): These medications may reduce the effectiveness of Acebutolol in lowering blood pressure.

Insulin and oral diabetes medications (e.g., Metformin, Glipizide): Acebutolol can mask the symptoms of low blood sugar, making it harder to recognize hypoglycemia.

Acebutolol in Pregnancy

Is it Safe to Take Acebutolol During Pregnancy?

Acebutolol is classified as a pregnancy category B medication, meaning animal studies have not shown harm to the fetus, but there are no well-controlled studies in pregnant women. It should only be used during pregnancy if the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, discuss the risks and benefits of Acebutolol with your healthcare provider. You can also schedule a telemedicine appointment with one of our providers to review your treatment options.

Acebutolol While Breastfeeding

Is it Safe to Take Acebutolol While Breastfeeding?

Acebutolol is excreted in breast milk, which may pose a risk of side effects in the nursing infant, such as a slow heart rate or low blood pressure. If you are breastfeeding, talk to your healthcare provider about whether to continue Acebutolol. In some cases, an alternative medication may be recommended. You can consult one of our telemedicine providers to discuss your options.

Estimated Cost of Acebutolol Medication

The cost of Acebutolol can vary depending on the pharmacy and location. Without insurance, a 30-day supply of Acebutolol (200 mg) using a GoodRx coupon is estimated to cost between $10 and $15. Prices may fluctuate, so it’s a good idea to check with your pharmacy or use a coupon service like GoodRx for the most accurate pricing.

Possible Alternatives to Acebutolol

If Acebutolol is not the right fit for you, there are other treatment options available for various conditions. Always consult your healthcare provider before making any changes to your treatment plan, or schedule a telemedicine visit with one of our providers to explore these alternatives.

1. Hypertension (High Blood Pressure): Alternatives include other beta-blockers (e.g., Metoprolol), ACE inhibitors (e.g., Lisinopril), or lifestyle changes such as reducing sodium intake, exercising regularly, and managing stress.
2. Angina (Chest Pain): Other medications like calcium channel blockers (e.g., Amlodipine) or nitrates (e.g., Nitroglycerin) may be considered. Lifestyle changes such as quitting smoking and maintaining a healthy diet can also help.
3. Arrhythmia (Irregular Heartbeat): Medications like Amiodarone or Flecainide may be used. In some cases, procedures like cardioversion or ablation may be recommended.
4. Heart Failure: ACE inhibitors (e.g., Enalapril), diuretics (e.g., Furosemide), or lifestyle changes such as reducing fluid intake and monitoring weight may be helpful.
5. Myocardial Infarction (Heart Attack): Other beta-blockers like Atenolol or medications such as aspirin and statins may be used to reduce the risk of future heart attacks.
6. Tachycardia (Fast Heart Rate): Calcium channel blockers (e.g., Verapamil) or antiarrhythmic medications may be considered. Stress management techniques can also help reduce episodes.
7. Atrial Fibrillation: Anticoagulants (e.g., Warfarin) or antiarrhythmic medications may be used. In some cases, procedures like electrical cardioversion may be necessary.
8. Anxiety: Non-beta-blocker medications like selective serotonin reuptake inhibitors (SSRIs) or therapy techniques such as cognitive behavioral therapy (CBT) may be effective.
9. Migraine: Other medications such as triptans (e.g., Sumatriptan) or preventive medications like Topiramate may be considered. Lifestyle changes like avoiding migraine triggers can also help.
10. Hyperthyroidism: Medications like Methimazole or radioactive iodine treatment may be used to manage thyroid hormone levels.

Recent Updates on Acebutolol Research

Recent studies have investigated the long-term effects of beta-blockers like Acebutolol in managing cardiovascular conditions. One area of interest is the potential for beta-blockers to reduce inflammation in patients with heart disease. Additionally, ongoing research is exploring the use of beta-blockers in individuals with anxiety disorders, as they may help manage physical symptoms such as a rapid heart rate. However, more studies are needed to confirm these benefits. Always consult your healthcare provider before making any changes to your medication or treatment plan. If you have questions about the latest research, feel free to schedule a telemedicine appointment with one of our providers.

James Kingsley

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