The Kingsley Clinic

Wart Treatment: Causes, Types, and Effective Removal Options

Introduction

Warts are a common skin condition that has affected people for centuries. These small, rough growths can appear on various parts of the body, including the hands, feet, and face. Warts are caused by specific strains of the human papillomavirus (HPV), which infects the top layer of the skin. While generally harmless, warts can be unsightly, uncomfortable, and even painful, depending on their location and size. Over time, warts have been treated using a wide range of methods, from traditional folk remedies to modern medical techniques.

This article provides a comprehensive overview of warts, including their risk factors, symptoms, diagnostic methods, available treatments, and home care options. By understanding these aspects, patients can make informed decisions about managing their condition and seeking appropriate care.

What Are Warts?

Warts are small, benign skin growths caused by the human papillomavirus (HPV). This article will cover key aspects such as risk factors, symptoms, diagnostic tests, medications, procedures for wart treatment, and home care tips to help manage symptoms.

Types of Warts and Their Description

Warts are non-cancerous skin growths that develop when HPV infects the skin. The virus enters the body through small cuts or breaks, leading to wart formation. There are several types of warts, including common warts (verruca vulgaris), plantar warts (which occur on the soles of the feet), and flat warts (which are smaller and smoother).

Warts typically begin as small, rough bumps on the skin. Over time, they may grow larger and develop a grainy surface. Some warts can be painful, especially those located on pressure points like the soles of the feet. In some cases, warts may disappear on their own, but this process can take months or even years.

Warts are widespread, affecting about 10% of the population at any given time. They are most common among children and young adults, though people of all ages can develop them. The virus that causes warts is highly contagious and can spread through direct contact with a wart or surfaces exposed to the virus, such as towels or floors.

Risk Factors for Developing Warts

Lifestyle Risk Factors

Certain lifestyle factors can increase the risk of developing warts. One of the most significant is direct contact with someone who has warts or with surfaces exposed to the virus. For example, walking barefoot in public areas like swimming pools or locker rooms can raise the likelihood of contracting plantar warts. Sharing personal items like towels, razors, or shoes with someone who has warts can also spread the virus.

Frequent exposure to moisture is another risk factor. Warts thrive in warm, moist environments, so individuals who sweat excessively or frequently handle wet objects (such as swimmers or dishwashers) may be more prone to developing warts.

Additionally, habits like nail-biting or picking at hangnails increase the risk of developing warts on the fingers and hands, as the virus can enter through small cuts or abrasions caused by these behaviors.

Medical Risk Factors

Certain medical conditions and treatments can also increase the risk of developing warts. People with weakened immune systems, such as those with HIV/AIDS or individuals undergoing immunosuppressive therapy (e.g., organ transplant recipients), are more susceptible to warts because their immune systems are less able to fight off the HPV virus.

Individuals with a history of eczema or other chronic skin conditions may also be more prone to warts, as their skin barrier is compromised, making it easier for the virus to enter. People with diabetes may be at higher risk, particularly for plantar warts, as their immune systems may be less effective in fighting infections in the feet.

Genetic and Age-Related Risk Factors

Genetics can play a role in determining an individual’s susceptibility to warts. Some people may have a genetic predisposition that makes them more likely to develop warts when exposed to HPV. This could be due to variations in the immune system that affect how the body responds to the virus.

Age is another important factor. Warts are most common in children and young adults, likely because their immune systems are still developing and may not be as effective at fighting off HPV. However, warts can occur at any age, and older adults with weakened immune systems may also be at higher risk.

In summary, while warts are common and generally harmless, certain lifestyle choices, medical conditions, and genetic factors can increase the likelihood of developing them. Understanding these risk factors can help individuals take steps to reduce their chances of contracting warts and seek appropriate treatment if they do develop.

Clinical Manifestations of Warts

Rough Texture

Warts often have a rough texture, present in about 90% of cases. This roughness is due to the thickening of the skin caused by HPV, which triggers an overproduction of keratin, a protein that forms the outer skin layer. The rough surface can feel like sandpaper and varies in severity depending on the type and location of the wart. This texture is usually more pronounced in common warts (verruca vulgaris) and plantar warts.

Raised Surface

Approximately 85% of warts exhibit a raised surface. The raised appearance is caused by the rapid growth of skin cells in response to the viral infection. The wart’s height can vary from a slight bump to a more pronounced protrusion. This characteristic is often seen in common and plantar warts, but the degree of elevation can differ depending on the wart’s location and subtype. Raised warts are more common in younger individuals and those with weakened immune systems.

Small Bumps

Small bumps are a hallmark of warts, occurring in about 80% of cases. These bumps can be flesh-colored, white, or slightly darker than the surrounding skin. They are typically round or oval and may appear singly or in clusters. The bumps are caused by localized skin thickening in response to HPV. Flat warts, more common in children and adolescents, tend to present as smaller, smoother bumps compared to other types of warts.

Skin Discoloration

Warts can cause skin discoloration in approximately 70% of cases. This discoloration may range from flesh-colored to brown, gray, or even black, depending on the type of wart and the individual’s skin tone. The discoloration is due to increased blood supply to the wart and the accumulation of dead skin cells. Plantar warts, in particular, may have small black dots, which are clotted blood vessels. Discoloration is often more noticeable in warts that have been present for a long time.

Pain or Tenderness

Pain or tenderness is reported in about 60% of wart cases, especially in plantar warts located on the soles of the feet. The pain occurs because the wart presses into deeper skin layers, irritating nerve endings. This symptom is more common in warts subjected to pressure, such as those on the feet or hands. Pain can worsen over time if the wart grows or is located in an area that experiences frequent friction or weight-bearing.

Itching

Itching is a less common symptom, affecting around 30% of wart patients. Itching occurs due to the body’s immune response to the HPV infection. The immune system attempts to fight off the virus, leading to inflammation and skin irritation. Itching is more likely in warts that are healing or exposed to friction, such as those on the hands or feet. Scratching the wart can lead to further irritation and may increase the risk of spreading the virus to other areas of the skin.

Bleeding

Bleeding is seen in about 25% of warts, particularly when scratched or picked at. Warts have a rich blood supply, and trauma to the wart can cause it to bleed. Plantar warts are especially prone to bleeding due to the pressure they endure from walking or standing. Bleeding can also occur if the wart is located in an area that experiences frequent friction, such as the fingers or toes. It’s important to avoid picking at warts to prevent bleeding and the spread of the virus.

Wart Clusters

Wart clusters, or multiple warts appearing in close proximity, occur in about 40% of cases. This is more common in plantar and flat warts. Clusters form when the virus spreads to nearby skin, leading to the development of new warts. These clusters can be more difficult to treat than single warts, as the virus is more widespread. Clusters are more likely to occur in individuals with weakened immune systems or those who frequently touch or scratch their warts.

Flat Warts

Flat warts, also known as verruca plana, are seen in about 20% of wart cases. They are typically smaller and smoother than other types of warts and are often found on the face, neck, or hands. Flat warts are more common in children and adolescents and tend to appear in clusters. The flat appearance is due to the way the virus affects the skin’s top layer, causing a less pronounced thickening compared to other types of warts.

Plantar Warts

Plantar warts are a specific type of wart that occurs on the soles of the feet and are present in about 30% of wart cases. These warts can be painful due to the pressure exerted on them while walking or standing. Plantar warts often have a rough, thickened surface and may contain small black dots, which are clotted blood vessels. They can appear singly or in clusters and are more common in individuals who walk barefoot in communal areas, such as swimming pools or locker rooms.

Treatment Options for Warts

Medications for Wart Treatment

Salicylic Acid

Salicylic acid is a topical treatment that works by softening the layers of skin, allowing the wart to gradually peel away. It is available over-the-counter in various forms, including gels, pads, and liquids.

Often used for both common and plantar warts, it is considered a first-line treatment due to its accessibility and ease of use. Patients are typically advised to apply the acid daily, often after soaking the wart in warm water to soften the skin.

With consistent application, salicylic acid may take several weeks to months to fully remove the wart. Gradual improvement is expected as the wart shrinks and eventually disappears.

Imiquimod

Imiquimod is a cream that stimulates the immune system to fight the virus responsible for the wart. It is most commonly prescribed for genital warts but can also be used for other types.

Applied directly to the wart several times a week, Imiquimod is generally reserved for warts that have not responded to other treatments.

Results may be seen within weeks to months, though complete wart removal may take longer. The immune response it triggers can also help reduce the likelihood of recurrence.

Podophyllin

Podophyllin is a plant-based resin applied to warts to destroy the affected tissue, most commonly used for genital warts.

Due to its potential toxicity, podophyllin is administered by a healthcare provider and is not recommended for home use. It is typically reserved for warts that have not responded to less aggressive treatments.

Improvement may be seen after a few applications, but multiple treatments may be necessary for complete removal.

Cantharidin

Cantharidin is a blistering agent that causes the skin beneath the wart to blister, lifting the wart away. It is often combined with other chemicals to enhance its effectiveness.

This treatment is applied by a healthcare provider and is typically used for warts that have not responded to over-the-counter treatments. It is not available for home use.

Warts treated with cantharidin usually fall off within a week or two after blistering, though multiple treatments may be required for complete removal.

Trichloroacetic Acid (TCA)

Trichloroacetic acid (TCA) is a chemical peel that burns off wart tissue, particularly effective for genital warts and warts in sensitive areas.

Applied by a healthcare provider, TCA is used when other treatments, such as salicylic acid, have failed or are unsuitable for the wart’s location.

Several applications may be needed, but warts typically begin to diminish within weeks of treatment.

Bleomycin

Bleomycin is an injectable chemotherapy drug that targets cells infected by the wart virus, used for severe or resistant warts.

Administered by a healthcare provider, it is not a first-line option due to its invasive nature and potential side effects.

Improvement may be seen after a few injections, but multiple treatments may be necessary. The wart may shrink and disappear over several weeks.

5-Fluorouracil

5-Fluorouracil is a topical chemotherapy cream that inhibits cell growth, used for warts resistant to other treatments, particularly flat warts.

Applied directly to the wart, it is typically used when other topical treatments have failed. It is not a first-line treatment due to potential side effects, including skin irritation.

Gradual improvement can be expected over several weeks to months, with the wart shrinking and eventually disappearing.

Procedures for Wart Removal

Cryotherapy

Cryotherapy involves freezing the wart with liquid nitrogen, causing the wart tissue to die and eventually fall off. It is one of the most common procedures for wart removal.

Typically performed by a healthcare provider, cryotherapy is often used when over-the-counter treatments like salicylic acid have failed. It can treat various types of warts, including common, plantar, and genital warts.

Multiple sessions may be needed, but warts usually begin to shrink and fall off within weeks of treatment.

Laser Therapy

Laser therapy uses focused light to burn off wart tissue and is usually reserved for warts resistant to other treatments.

Performed by a healthcare provider, it is not a first-line treatment due to its cost and potential for scarring. It is often used for large or stubborn warts that have not responded to other therapies.

Warts may disappear after one or more sessions, though healing can take weeks, and there is a small risk of scarring.

Duct Tape Occlusion Therapy

Duct tape occlusion therapy involves covering the wart with duct tape to suffocate it and stimulate the immune system to attack the virus.

Often used as a home remedy, it can also be recommended by healthcare providers. It is a low-cost, non-invasive option that can be tried before more aggressive treatments.

Improvement may be seen after several weeks of consistent use, though results can vary, and the wart may return if the virus is not completely eradicated.

Improving Warts and When to Seek Medical Help

Many patients try home remedies before seeking medical treatment for warts. Popular options include applying apple cider vinegar, garlic, banana peel, tea tree oil, or vitamin E directly to the wart. These remedies are believed to have antiviral or skin-healing properties, but their effectiveness varies, and they are not strongly supported by scientific evidence. Salicylic acid, castor oil, aloe vera, and onion are also common home treatments.

While home remedies may help with small or new warts, it is important to seek medical advice if the wart persists, grows, or causes pain. Telemedicine offers a convenient way to consult with a healthcare provider from home. Through telemedicine, a doctor can assess your wart, recommend treatments, and prescribe medications if necessary.

Living with Warts: Tips for a Better Quality of Life

Warts can be uncomfortable and embarrassing, but there are steps you can take to manage them and improve your quality of life. Avoid picking or scratching the wart, as this can spread the virus to other parts of your body or to others. Keep the wart covered with a bandage or duct tape to reduce the risk of spreading it. If the wart is painful, especially on the feet, consider using cushioning pads or insoles to relieve pressure.

Consistency with your treatment plan is key to getting rid of warts. Whether using over-the-counter treatments, home remedies, or prescription medications, follow your healthcare provider’s instructions carefully. If you have multiple warts or warts that keep returning, it may be helpful to consult a healthcare provider through telemedicine to explore advanced treatment options.

Conclusion

Warts are a common skin condition caused by the human papillomavirus (HPV). While generally harmless, they can be unsightly and uncomfortable. Early diagnosis and treatment are important to prevent the spread of warts to other areas of your body or to others. With a variety of treatment options available, from over-the-counter medications to advanced procedures, warts can often be successfully treated.

If you are struggling with warts, our telemedicine practice is here to help. Through virtual consultations, we can assess your condition and recommend the best treatment plan for you. Don’t wait—schedule an appointment today to start your journey toward clearer skin.

James Kingsley
James Kingsley

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