Medication Profile: Octreotide
Summary or Key Points
Octreotide is a versatile medication used in the management of several conditions, most notably those related to hormonal imbalances. This article offers detailed information about Octreotide, including indications, dosing, side effects, contraindications, and more. As always, consult your healthcare provider before making any changes to your medication regimen. Our telemedicine services make this consultation accessible from the comfort of your home.
Names of Medication
US Brand Name: Sandostatin (Octreotide)
The ‘generic name’ is the official medical name for the active ingredient of the medicine. In this case, the generic name is ‘Octreotide,’ which is in parentheses.
Pharmacologic Category
Octreotide belongs to the pharmacologic category of somatostatin analogs.
Dosing
Octreotide is indicated for the treatment of:
- Acromegaly: Initial dose 50 mcg three times a day, with a range of 100-500 mcg three times a day.
- Carcinoid Syndrome and Vasoactive Intestinal Peptide Tumor (VIPoma): 100-600 mcg/day in 2-4 divided doses.
- Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs), Pituitary Adenomas, Esophageal Varices, Dumping Syndrome: Dosing varies widely based on individual patient factors and specific circumstances.
- Diabetic Retinopathy: Dosing is off-label and should be determined by a healthcare provider.
Always consult your healthcare provider before changing your medication dose. Our practice offers telemedicine consultations for convenient access to care.
Dosage Forms and Strengths
Octreotide is available in various forms and strengths:
- Injection: 50 mcg/1mL, 100 mcg/1mL, 500 mcg/1mL
- Long-acting injection: 10 mg, 20 mg, 30 mg
Administration Instructions
Octreotide is administered as a subcutaneous or intravenous injection. Follow your healthcare provider’s instructions regarding administration.
Adverse Reactions and Side Effects
Common side effects of Octreotide may include abdominal discomfort, nausea, diarrhea, gallstones, and injection site reactions. Always notify your healthcare provider of any side effects. Telemedicine consultations with our practice can provide further guidance.
Contraindications
Contraindications are conditions or factors that serve as reasons not to take a certain medication. Octreotide is contraindicated in individuals with hypersensitivity to Octreotide or any component of the formulation. It should be used with caution in patients with gallbladder, heart, kidney, or liver disease, or in patients with diabetes mellitus.
Drug to Drug Interactions
Octreotide may interact with other medications including:
- Insulin or other diabetes medications (e.g., Glipizide, Glucotrol)
- Cyclo sporine (Neoral, Sandimmune)
- Bromocriptine (Cycloset, Parlodel)
- Quinidine (Quinidex, Quinaglute, Quin-Release)
Octreotide in Pregnancy
Octreotide should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. Always consult your healthcare provider if you are pregnant or plan to become pregnant while taking this medication.
Octreotide while Breastfeeding
It’s not known whether Octreotide is excreted in human milk. Given the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Always consult your healthcare provider during this decision-making process.
Estimated Cost of Medication
The estimated cost of a 30-day supply of Octreotide (100 mcg three times a day) without insurance, using a GoodRX coupon, is approximately $600-$800. However, prices may vary depending on location and pharmacy.
Possible Alternatives
For Acromegaly, alternative treatments may include dopamine agonists or growth hormone receptor antagonists. For Carcinoid Syndrome and VIPoma, other somatostatin analogs or interferon alfa may be used. In the case of GEP-NETs, Pituitary Adenomas, Esophageal Varices, and Dumping Syndrome, treatment options may vary widely based on individual patient factors and specific circumstances. For Diabetic Retinopathy, alternative treatments include laser surgery or vitrectomy. Always discuss these alternatives with your healthcare provider before making any changes to your treatment plan. Telemedicine consultations are available with our providers.
Recent Updates on Octreotide Research
As of 2023, researchers continue to explore Octreotide’s potential benefits for other hormonal imbalances and tumor types. These studies are in the early stages, and further investigation is needed before any new indications can be recommended. Patients interested in learning more about these developments are encouraged to consult with their healthcare provider. Telemedicine consultations are available with our providers.
Remember, always stay informed about your medications, and don’t hesitate to reach out to your healthcare provider with any questions or concerns. At our practice, telemedicine consultations are available to provide you the care you need, right in the comfort of your own home.
Brief Legal Disclaimer
This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.
While every effort has been made to ensure the accuracy of this information, medicine is a constantly evolving field, and changes may occur that may not be reflected here. Please discuss any concerns or questions you have about your health or medications with your healthcare provider.
Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.