Fexofenadine 180 mg: Uses, Dosage, and Side Effects Explained

Summary of Key Points

Fexofenadine is a non-drowsy antihistamine commonly used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and hives. It is often prescribed for conditions like seasonal allergies, allergic rhinitis, and chronic urticaria. Fexofenadine works by blocking histamine, a substance in the body that triggers allergic reactions. Always consult your healthcare provider before starting or adjusting your dose. You may also consider scheduling a telemedicine visit with one of our providers for personalized advice.

Names of Medication

US Brand Name: Allegra

Generic Name: Fexofenadine

The generic name refers to the active ingredient in the medication, while the brand name is assigned by the manufacturer. In this case, “Fexofenadine” is the generic name.

Pharmacologic Category

Antihistamines, Second Generation

Fexofenadine Dosage

Fexofenadine is prescribed to treat various allergic conditions. Below are the recommended doses for adults. Always consult your doctor before making any changes to your dosage, and feel free to schedule a telemedicine visit with one of our providers for further guidance.

1. Allergic Rhinitis (Seasonal Allergies, Hay Fever): 60 mg twice daily or 180 mg once daily. The duration of treatment depends on the length of the allergy season or exposure to allergens.
2. Chronic Urticaria (Hives): 60 mg twice daily or 180 mg once daily. Treatment is typically long-term, depending on how persistent the symptoms are.
3. Allergic Conjunctivitis (Itchy/Watery Eyes): 60 mg twice daily or 180 mg once daily. Continue treatment as long as symptoms persist.
4. Skin Allergies (Including Insect Bite Allergies): 60 mg twice daily or 180 mg once daily. The duration of treatment varies based on symptom relief.
5. Pet Allergies: 60 mg twice daily or 180 mg once daily. Continue treatment as long as exposure to the allergen persists.
6. Dust Mite Allergies: 60 mg twice daily or 180 mg once daily. The length of treatment depends on ongoing exposure to the allergen.
7. Mold Allergies: 60 mg twice daily or 180 mg once daily. Continue treatment as long as exposure to mold persists.

Dosage Forms and Strengths

Fexofenadine is available in the following forms and strengths:

1. Tablets: 60 mg, 180 mg
2. Oral Suspension: 30 mg/5 mL
3. Orally Disintegrating Tablets: 30 mg

Administration Instructions for Fexofenadine

Fexofenadine should be taken with water and can be taken with or without food. Avoid taking it with fruit juices (such as orange, grapefruit, or apple juice), as they may reduce the absorption of the medication. If using the orally disintegrating tablets, allow the tablet to dissolve on your tongue without chewing, then swallow. Always follow your healthcare provider’s instructions for taking this medication.

Fexofenadine Side Effects and Adverse Reactions

Like all medications, Fexofenadine may cause side effects. Most are mild, but some can be more serious. If you experience any severe reactions, contact your healthcare provider immediately or schedule a telemedicine appointment with one of our providers.

1. Common Side Effects (1-10%): Headache, dizziness, nausea, dry mouth, fatigue. These side effects are usually mild and tend to resolve on their own.
2. Less Common Side Effects (0.1-1%): Insomnia, nervousness, or sleep disturbances. If these persist, consult your doctor.
3. Rare Side Effects (<0.1%): Allergic reactions such as rash, itching, or swelling. Seek medical attention if you experience these symptoms.

Contraindications for Fexofenadine

A contraindication is a specific condition in which a medication should not be used because it may be harmful. It’s important to know if any of these apply to you before starting Fexofenadine.

1. Allergy to Fexofenadine: If you have had an allergic reaction to Fexofenadine or any of its ingredients, you should not take this medication. An allergic reaction could cause symptoms like rash, itching, swelling, or difficulty breathing.
2. Severe Kidney Disease: Fexofenadine is processed by the kidneys. If you have severe kidney disease, the medication may not be cleared from your body properly, increasing the risk of side effects.
3. Children Under 6 Months: Fexofenadine has not been studied in children younger than 6 months, and its safety in this age group is not established.

Drug Interactions with Fexofenadine

Fexofenadine can interact with other medications, which may affect its efficacy or increase the risk of side effects. Be sure to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, vitamins, and supplements.

1. Antacids containing aluminum or magnesium (e.g., Maalox, Mylanta): These can reduce the absorption of Fexofenadine, making it less effective. It’s recommended to take Fexofenadine at least 2 hours before or after taking these antacids.
2. Ketoconazole (Nizoral): This antifungal medication can increase Fexofenadine levels in your blood, potentially leading to more side effects.
3. Erythromycin (Ery-Tab): This antibiotic can also increase Fexofenadine levels in your system, which may raise the risk of side effects.

Fexofenadine in Pregnancy

Is it safe to take Fexofenadine when pregnant?

Fexofenadine, commonly known by the brand name Allegra, is classified as a Category C drug by the FDA for use during pregnancy. This means that while animal studies have shown some potential risk to the fetus, there are no well-controlled studies in pregnant women. In certain situations, the potential benefits of taking Fexofenadine may outweigh the risks. If you are pregnant or planning to become pregnant, it’s essential to consult your healthcare provider to determine whether Fexofenadine is a suitable option for you. You can also schedule a telemedicine visit with one of our providers to discuss your treatment options.

Fexofenadine while Breastfeeding

Is it safe to take Fexofenadine while breastfeeding?

Fexofenadine is generally considered safe to use while breastfeeding, as only small amounts of the medication pass into breast milk. However, it’s always best to consult your healthcare provider before taking any medication while nursing. They can help you weigh the benefits and potential risks based on your individual circumstances.

Estimated Cost of Fexofenadine 180 mg

The cost of a 30-day supply of Fexofenadine 180 mg without insurance can vary depending on the pharmacy and location. With a GoodRx coupon, the estimated price for a 30-day supply of Fexofenadine (180 mg) typically ranges from $10 to $15. Prices may fluctuate, so it’s a good idea to check with your local pharmacy or use a discount program like GoodRx to find the most affordable option.

Possible Alternatives to Fexofenadine

If Fexofenadine isn’t the right medication for you, there are other treatment options and lifestyle changes that may help manage your symptoms. Always consult your healthcare provider before making any changes to your treatment plan. You can also schedule a telemedicine visit with one of our providers to explore these alternatives.

Alternatives for Allergic Rhinitis, Seasonal Allergies, and Hay Fever

Other options include antihistamines like Loratadine (Claritin) or Cetirizine (Zyrtec), nasal corticosteroids such as Fluticasone (Flonase), or lifestyle adjustments like avoiding known allergens, using air purifiers, and keeping windows closed during high pollen seasons.

Alternatives for Chronic Urticaria (Hives)

Other antihistamines, such as Cetirizine (Zyrtec) or Hydroxyzine (Atarax), may be effective. In more severe cases, medications like Omalizumab (Xolair) could be considered. Avoiding known triggers is also an important part of managing symptoms.

Alternatives for Allergic Conjunctivitis

Antihistamine eye drops, such as Ketotifen (Zaditor) or Olopatadine (Pataday), can provide relief. Additionally, avoiding allergens and using cold compresses may help alleviate symptoms.

Alternatives for Skin Allergies and Insect Bite Allergies

Topical corticosteroids like Hydrocortisone cream or oral antihistamines such as Diphenhydramine (Benadryl) may be effective. Preventing exposure to allergens or insects is also key to managing these types of allergies.

Alternatives for Pet Allergies

In addition to antihistamines, regular cleaning, using HEPA filters, and keeping pets out of bedrooms can help reduce symptoms.

Alternatives for Dust Mite Allergies

Using dust mite-proof bedding, washing sheets in hot water, and vacuuming with a HEPA filter can help minimize symptoms. Antihistamines or nasal corticosteroids may also be beneficial.

Alternatives for Mold Allergies

Reducing indoor humidity, using dehumidifiers, and cleaning moldy areas can help manage mold allergies. Medications like antihistamines or nasal corticosteroids may also be recommended.

Recent Updates on Fexofenadine Research

Recent studies continue to support the safety and effectiveness of Fexofenadine for treating allergic conditions such as allergic rhinitis and chronic urticaria. Ongoing research is exploring the use of Fexofenadine in combination with other medications to enhance its effectiveness, particularly in patients with more severe allergic reactions. Additionally, studies are being conducted to better understand the long-term safety of Fexofenadine in children and older adults. As new findings emerge, it’s always a good idea to stay informed and consult your healthcare provider about any updates that may impact your treatment plan.

James Kingsley

Learn More