The Kingsley Clinic

Mometasone: Uses, Dosage, and Side Effects Overview

Summary of Key Points

Mometasone is a corticosteroid commonly prescribed to manage various inflammatory conditions, such as allergic rhinitis, asthma, eczema, and psoriasis. It works by reducing inflammation and suppressing the immune response in the affected areas. Mometasone is available in several forms, including nasal sprays, inhalers, and topical creams. While generally well-tolerated, it may cause side effects in some individuals. Always consult your healthcare provider before starting or adjusting your dose.

Names of Medication

Nasonex (Mometasone)

Asmanex (Mometasone)

Elocon (Mometasone)

Sinuva (Mometasone)

The generic name refers to the active ingredient, while the brand name is assigned by the manufacturer. In this case, Mometasone is the generic name, listed in parentheses.

Pharmacologic Category

Fluticasone

Beclomethasone

Budesonide

Triamcinolone

Mometasone Dosing Guidelines

Allergic Rhinitis (Nasal Allergies): For adults, the typical dose is 2 sprays (50 mcg each) in each nostril once daily. The duration of treatment depends on the severity of symptoms and should be discussed with your healthcare provider.

Asthma: For adults, the recommended dose ranges from 220 mcg to 440 mcg inhaled twice daily. The dose may be adjusted based on the severity of asthma. Always consult your doctor before making any changes to your dosage.

Eczema, Psoriasis, and Dermatitis: Apply a thin layer of Mometasone cream or ointment (0.1%) to the affected area once daily. The length of treatment varies depending on the condition and response to the medication.

Nasal Polyps: For adults, the typical dose is 2 sprays (50 mcg each) in each nostril twice daily. Treatment may continue for several months, depending on the severity of the condition.

Chronic Rhinosinusitis: The recommended dose is 2 sprays (50 mcg each) in each nostril twice daily. Treatment should continue as directed by your healthcare provider.

Urticaria (Hives): Mometasone cream or ointment (0.1%) can be applied once daily to the affected area. The duration of treatment depends on the severity of the condition.

Conjunctivitis: Mometasone is not typically used for conjunctivitis. Consult your healthcare provider for appropriate treatment options.

Inflammatory Bowel Disease (IBD): Mometasone is not commonly used for IBD. Consult your healthcare provider for alternative treatments.

Always consult your healthcare provider before adjusting your dose. You can schedule a telemedicine appointment with one of our providers for personalized advice.

Dosage Forms and Strengths of Mometasone

Nasal Spray: 50 mcg per spray

Inhaler: 110 mcg, 220 mcg per actuation

Cream: 0.1%

Ointment: 0.1%

Lotion: 0.1%

Implant (for nasal polyps): 1350 mcg

How to Use Mometasone: Administration Instructions

For nasal sprays, gently shake the bottle before use and prime it if necessary (usually by spraying into the air). Insert the nozzle into your nostril and spray while breathing in gently. Avoid blowing your nose immediately after use. For inhalers, follow the specific instructions provided with the device. For topical forms like Mometasone cream or ointment, apply a thin layer to the affected area and rub it in gently. Always wash your hands after applying the medication unless you are treating your hands.

Mometasone Side Effects and Adverse Reactions

Common Side Effects: These may include headache, sore throat, and nasal irritation. These side effects are usually mild and temporary.

Less Common Side Effects: These can include nosebleeds, cough, and upper respiratory infections. If these symptoms persist, consult your healthcare provider.

Rare but Serious Side Effects: In rare cases, Mometasone can cause vision problems, severe allergic reactions, or adrenal suppression. Seek immediate medical attention if you experience any of these symptoms.

Contraindications for Mometasone Use

A contraindication is a specific situation or condition where a particular treatment or medication should not be used because it may cause harm. If you have any of the following conditions, you should not take Mometasone, or you should discuss your situation with a healthcare provider before starting the medication.

Allergy to Mometasone or other corticosteroids: If you have a known allergy to Mometasone or other corticosteroids, using this medication could cause a severe allergic reaction, including rash, itching, swelling, or difficulty breathing.

Untreated fungal, bacterial, or viral infections: Mometasone can weaken your immune system, making it harder for your body to fight infections. If you have an untreated infection, using Mometasone could make the infection worse.

Active tuberculosis (TB): Mometasone can suppress your immune system, which may allow TB to become active or worsen if you have a history of TB or a current infection.

Severe liver disease: Mometasone is processed by the liver, and if your liver is not functioning properly, the medication may not be metabolized correctly, leading to potential side effects or toxicity.

Drug Interactions with Mometasone

Some medications can interact with Mometasone, either increasing the risk of side effects or reducing the effectiveness of one or both drugs. Inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. Here are some common medications that may interact with Mometasone:

Ritonavir (Norvir): This antiviral medication used to treat HIV can increase the levels of Mometasone in your body, raising the risk of side effects.

Ketoconazole (Nizoral): An antifungal medication that may increase the concentration of Mometasone in your bloodstream, potentially leading to more side effects.

Cyclosporine (Neoral, Sandimmune): This immunosuppressant may interact with Mometasone, increasing the risk of infections or other immune-related issues.

Other corticosteroids (Prednisone, Hydrocortisone): Taking multiple corticosteroids can increase the risk of side effects, such as weakened immune function or hormonal imbalances.

Mometasone in Pregnancy

Is it safe to take Mometasone when pregnant?

The safety of Mometasone during pregnancy has not been fully established. While animal studies suggest there may be some risk to the fetus, data on its use in pregnant humans is limited. Mometasone should only be used during pregnancy if the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, it is important to consult your healthcare provider before using Mometasone. Our telemedicine providers are available to discuss your options and help you make an informed decision.

Mometasone While Breastfeeding

Is it safe to take Mometasone while breastfeeding?

There is limited information on whether Mometasone passes into breast milk. Since corticosteroids can be absorbed into the bloodstream and may affect a nursing infant, caution is advised. If you are breastfeeding, it’s essential to talk to your healthcare provider about the potential risks and benefits of using Mometasone. You can schedule a telemedicine appointment with one of our providers to discuss your specific situation.

Estimated Cost of Mometasone Medication

The cost of a 30-day supply of Mometasone without insurance can vary depending on the form (e.g., Mometasone nasal spray, inhaler, or topical cream). Using a GoodRx coupon, the cost for a 30-day supply of Mometasone nasal spray typically ranges from $40 to $60. Prices may vary based on your location and the pharmacy you use.

Possible Alternatives to Mometasone

If Mometasone is not suitable for you, or if you are exploring alternative treatments, several options are available. Always discuss any changes to your treatment plan with your healthcare provider before making adjustments. Our telemedicine providers are here to help you explore these alternatives.

Allergic Rhinitis

Alternatives include antihistamines (e.g., Loratadine, Cetirizine), decongestants (e.g., Pseudoephedrine), or saline nasal sprays. Lifestyle changes, such as avoiding allergens and using air purifiers, may also provide relief.

Asthma

Other treatment options include inhaled corticosteroids (e.g., Fluticasone), long-acting beta-agonists (e.g., Salmeterol), or leukotriene modifiers (e.g., Montelukast). Regular exercise and avoiding asthma triggers can also help improve symptoms.

Eczema

Alternatives include topical calcineurin inhibitors (e.g., Tacrolimus), moisturizers, and avoiding irritants. Phototherapy may be considered for more severe cases. While Mometasone is commonly prescribed for eczema, alternatives should be explored if side effects occur.

Psoriasis

Other treatments include topical therapies (e.g., Calcipotriene), biologics (e.g., Adalimumab), or phototherapy. Lifestyle changes, such as stress management and maintaining a healthy weight, can also support symptom management.

Dermatitis

Alternatives include emollients, antihistamines, and avoiding known irritants or allergens. In some cases, oral corticosteroids may be prescribed for short-term use to manage flare-ups.

Nasal Polyps

Other treatments include nasal saline irrigation, oral corticosteroids, or surgery in more severe cases. Avoiding allergens and managing chronic sinusitis may help prevent polyps from worsening. Mometasone nasal spray is often used to manage nasal polyps effectively.

Chronic Rhinosinusitis

Alternatives include nasal saline sprays, antibiotics (if bacterial), or surgery. Managing allergies and avoiding irritants can also help reduce symptoms and prevent flare-ups.

Urticaria (Hives)

Antihistamines (e.g., Diphenhydramine, Cetirizine) are commonly used as alternatives. Identifying and avoiding known triggers, along with stress management, can also help reduce outbreaks.

Conjunctivitis

Alternatives include antihistamine eye drops, artificial tears, or avoiding allergens. For bacterial conjunctivitis, antibiotic eye drops may be prescribed to clear the infection.

Inflammatory Bowel Disease (IBD)

Alternatives include aminosalicylates (e.g., Mesalamine), immunosuppressants (e.g., Azathioprine), or biologics (e.g., Infliximab). Dietary changes and stress management may also help in managing symptoms and reducing flare-ups.

Recent Updates on Mometasone Research

Recent studies have focused on the long-term safety of Mometasone, particularly in managing chronic conditions like asthma and allergic rhinitis. A 2022 study found that Mometasone nasal spray was effective in reducing inflammation in patients with chronic rhinosinusitis without causing significant side effects. Another ongoing study is examining the use of Mometasone in combination with other biologic treatments for severe asthma, with early results suggesting improved lung function and fewer exacerbations.

As research continues, staying informed about new findings is important. If you have any questions about how the latest research might affect your treatment plan, our telemedicine providers are available to help you navigate your options.

James Kingsley
James Kingsley

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