Diltiazem: An Overview

Summary or Key Points

Diltiazem, a type of medication known as a calcium channel blocker, is widely used in the treatment of hypertension (high blood pressure), angina, and certain heart rhythm disorders such as atrial fibrillation. This article provides comprehensive information about its pharmacological category, dosage, possible side effects, and more. Consult your healthcare provider or one of our telemedicine specialists for more personalized advice.

Names of Medication

The medication is commonly known by its US brand name, Cardizem (Diltiazem).

The term ‘generic name’ is a standard, non-proprietary name for a medication. It’s often less complicated and easier to remember than brand names. The generic name for our discussed medication is denoted in parentheses as (Diltiazem).

Pharmacologic Category

Diltiazem belongs to a class of medications known as calcium channel blockers. Other medications in this category include Amlodipine (Norvasc), Verapamil (Calan, Isoptin), and Nifedipine (Procardia).

Dosing

Diltiazem is used in the treatment of several conditions. The following is the list of diseases along with the typical dose, frequency, and length of treatment. Remember to consult your doctor or one of our telemedicine providers before making any adjustments to your medication routine.

• High Blood Pressure (Hypertension): The typical starting dose is 180-240 mg once daily. Dosage can be adjusted according to the patient’s response.
• Angina: The usual dosage is 120-180 mg once daily. In some cases, doses may be increased up to 360 mg.
• Certain Heart Rhythm Disorders (such as atrial fibrillation): Dosages range from 120 to 360 mg daily.

Dosage Forms and Strengths

Diltiazem is available in multiple forms and strengths:

• Tablets (immediate release): 30 mg, 60 mg, 90 mg, 120 mg
• Capsules (extended release): 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg
• Injection: 5 mg/mL

Administration Instructions

Diltiazem can be taken with or without food. Swallow the capsules and tablets whole, do not crush, chew, or break them. For the injectable form, a healthcare professional will provide the medication. Always follow your healthcare provider’s instructions, and if you have any doubts, consult with one of our telemedicine providers.

Adverse Reactions and Side Effects

Like any medication, Diltiazem may cause side effects. It’s crucial to discuss these potential risks with your healthcare provider. Some of the side effects associated with Diltiazem are:

• Common side effects (occur in more than 1 in 100 people): headache, dizziness, feeling tired
• Uncommon side effects (occur in less than 1 in 100 people): feeling sick (nausea), stomach discomfort
• Rare side effects (occur in less than 1 in 1,000 people): skin rash, hives, itching

Always consult your healthcare provider or reach out to one of our telemedicine experts if you experience any side effects or have any concerns about your medication.

Contraindications

A contraindication is a condition or factor that makes a particular treatment or procedure potentially inadvisable. Diltiazem has several contraindications, including:

• Sick sinus syndrome: This is a group of heart rhythm problems due to malfunction of the sinus node, the heart’s primary pacemaker. Diltiazem can slow the heart rate further, exacerbating this condition.
• Second- or third-degree atrioventricular block: These are heart conditions where there’s a delay or blockage of electrical signals within the heart’s conducting system. Diltiazem can increase this blockage.
• Severe low blood pressure (hypotension): Diltiazem can lower blood pressure, which may lead to symptoms such as dizziness or fainting in individuals with already low blood pressure.

If you have any of these conditions, consult with your healthcare provider or one of our telemedicine experts before starting Diltiazem.

Drug to Drug Interactions

Several medications interact with Diltiazem. Notable examples include:

• Digoxin (Lanoxin)
• Beta-blockers like Metoprolol (Lopressor) and Atenolol (Tenormin)
• Statins like Simvastatin (Zocor) and Lovastatin (Mevacor)

These interactions may alter the way Diltiazem or the other medications work and increase the risk of side effects. Always inform your healthcare provider of all medications you’re taking.

Diltiazem in Pregnancy

While Diltiazem has been assigned to pregnancy category C by the FDA, it should only be used during pregnancy if the benefits outweigh the risks. Consult with your healthcare provider or our telemedicine experts to discuss your options.

Diltiazem while Breastfeeding

Diltiazem is excreted into human milk. While no side effects have been reported in breastfeeding infants, the benefits and potential risks should be discussed with your healthcare provider or our telemedicine experts.

Estimated Cost of Medication

The estimated cost of a 30-day supply of Diltiazem, using a GoodRx coupon and without insurance, is around $20 to $30, depending on the dosage and form of the medication.

Possible Alternatives

While medication may be necessary for managing conditions like hypertension, angina, or heart rhythm disorders, lifestyle changes and alternative treatments could also be beneficial. Some potential alternatives include:

• Hypertension: A healthy diet, regular exercise, stress management, and reducing sodium and alcohol intake can help manage blood pressure.
• Angina: Quitting smoking, maintaining a healthy weight, and controlling diabetes and other medical conditions can be beneficial.
• Heart Rhythm Disorders: Limiting caffeine and alcohol, managing stress, and maintaining a heart-healthy diet can aid in management.

Discuss these alternatives with your healthcare provider or one of our telemedicine specialists before making any changes to your treatment plan.

Recent Updates on Diltiazem Research

Research continues into the benefits and potential uses of Diltiazem. A recent study suggested that Diltiazem may help in the management of cocaine-related cardiovascular complications. However, further research is required. Stay in touch with your healthcare provider or our telemedicine experts for the most recent and relevant updates.

Brief Legal Disclaimer

This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.
Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.