US Brand Name: {Imdur}, {Monoket} (Isosorbide Mononitrate)

Pharmacologic Category:

{Nitrates}

Other medications in the same pharmacologic category: {Nitroglycerin}, {Isosorbide dinitrate}, and {Amyl nitrite}

Diseases Treated, Dosing, and Treatment Duration:

{Stable angina pectoris}: 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Unstable angina}: 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Variant angina} (Prinzmetal’s angina): 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Microvascular angina}: 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Chronic stable heart failure} (as an adjunct therapy): 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Acute myocardial infarction} (off-label use): 30-60 mg orally once daily, up to 240 mg/day in divided doses
{Pulmonary hypertension} (off-label use): 30-60 mg orally once daily, up to 240 mg/day in divided doses

Dosage Forms and Strengths:

Oral tablet: 10 mg, 20 mg, 30 mg, 60 mg Extended-release tablet: 30 mg, 60 mg, 120 mg

Administration Instructions:

Take the medication as directed by your healthcare provider, usually once daily. Extended-release tablets should not be crushed, chewed, or split. Swallow the tablet whole.

Adverse Reactions and Side Effects:

{Headache} (common): A painful sensation in the head. {Dizziness} (common): Feeling lightheaded or unsteady. {Flushing} (less common): Redness or warmth in the face or neck. {Low blood pressure} (hypotension) (less common): Abnormally low blood pressure levels. {Fainting} (syncope) (rare): Temporary loss of consciousness due to insufficient blood flow to the brain.

Contraindications:

Hypersensitivity to isosorbide mononitrate or other nitrates Concurrent use of PDE-5 inhibitors (e.g., {sildenafil} [Viagra], {tadalafil} [Cialis], {vardenafil} [Levitra])

Drug-to-Drug Interactions:

{Sildenafil} (Viagra): Can lead to a significant drop in blood pressure when used together. {Tadalafil} (Cialis): Can lead to a significant drop in blood pressure when used together. {Vardenafil} (Levitra): Can lead to a significant drop in blood pressure when used together.

Pregnancy:

Isosorbide mononitrate is classified as Pregnancy Category B. Animal studies have not demonstrated any harm to the fetus, but there are no adequate and well-controlled studies in pregnant women . Consult your healthcare provider before using this medication during pregnancy.

Breastfeeding:

There is limited information on the excretion of isosorbide mononitrate in human milk. Consult your healthcare provider before using this medication while breastfeeding.

Estimated price for a 30-day supply:

The estimated price of a 30-day supply of Isosorbide Mononitrate varies depending on the dose and form. Using a GoodRx coupon, the price ranges from $10 to $50. Prices may vary depending on location and specific pharmacy.

Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.