US Brand Name (Generic Name):

Eliquis ({Apixaban})

Pharmacologic Category:

Direct Oral Anticoagulant (DOAC) Other medications in the same category: {Rivaroxaban} ({Xarelto}), {Dabigatran} ({Pradaxa}), {Edoxaban} ({Savaysa})

Diseases Treated, Dosing, and Treatment Duration

{Deep Vein Thrombosis} (DVT): 10 mg twice daily for 7 days, followed by 5 mg twice daily.
{Pulmonary Embolism} (PE): 10 mg twice daily for 7 days, followed by 5 mg twice daily.
{Stroke Prevention} in {Atrial Fibrillation} (AFib): 5 mg twice daily or 2.5 mg twice daily (for patients meeting certain criteria).
{Venous Thromboembolism} (VTE) Prophylaxis following {Hip or Knee Replacement Surgery}: 2.5 mg twice daily, starting 12-24 hours after surgery (duration depends on the type of surgery).
{Recurrent Venous Thromboembolism Prevention}: 2.5 mg twice daily after completing at least 6 months of anticoagulant therapy.

Dosage Forms and Strengths:

Tablets: 2.5 mg and 5 mg.

Administration Instructions:

Take {Apixaban} with or without food. Swallow the tablet whole with a glass of water. If a dose is missed, take it as soon as possible on the same day and continue with the regular schedule.

Adverse Reactions and Side Effects:

{Bleeding} (including serious bleeding) (up to 16%): This may include minor bleeding (e.g., nosebleeds, gum bleeding) or serious bleeding (e.g., gastrointestinal bleeding, intracranial hemorrhage).
{Anemia} (2-9%): A decrease in red blood cells, which can cause fatigue, shortness of breath, and pale skin.
{Dizziness} (5-12%): A sensation of lightheadedness or feeling faint, which may increase the risk of falls.
{Headache} (3-10%): Pain or discomfort in the head or neck region.
{Cough} (1-10%): A dry, persistent cough resulting from the medication’s effect on the lungs.
{Hypotension} (1-5%): Low blood pressure, which can cause dizziness, lightheadedness, and fainting.
{Hyperkalemia} (1-5%): Elevated potassium levels in the blood, which can cause irregular heartbeats or other heart-related issues.
{Angioedema} (less than 1%): Swelling of the face, lips, tongue, or throat, which can cause difficulty breathing and requires immediate medical attention.

Contraindications:

Active pathological {bleeding} Severe hypersensitivity to {Apixaban} Patients on dual {antiplatelet therapy}

Drug to Drug Interactions:

{Ketoconazole} ({Nizoral}), {Itraconazole} ({Sporanox}): Increased risk of {bleeding} {Rifampin} ({Rifadin}, {Rimactane}): Decreased effectiveness of {Apixaban} {St. John’s Wort}: Decreased effectiveness of {Apixaban} {Aspirin} and other nonsteroidal anti-inflammatory drugs ({NSAIDs}): Increased risk of {bleeding}

Pregnancy:

Limited data on use during pregnancy; use only if the potential benefit outweighs the potential risk to the fetus.

Breastfeeding:

Limited data on the presence of {Apixaban} in human milk; use caution when administering to a nursing woman.

Estimate price of a 30-day supply without insurance and using a GoodRx coupon:

The estimated price for a 30-day supply of Eliquis (5 mg tablets) without insurance and using a GoodRx coupon is around $450-$500. Prices may vary depending on the pharmacy and the dosage strength.

Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.