US Brand Name: {Zebeta} ({Bisoprolol})

Pharmacologic category:

{Beta-blocker} Other medications in the same pharmacologic category: {Atenolol} ({Tenormin}), {Metoprolol} ({Lopressor}, {Toprol-XL}), {Propranolol} ({Inderal}, {InnoPran XL}), {Carvedilol} ({Coreg})

Diseases treated and dosing information:

{Hypertension} (high blood pressure): Initial dose of 5 mg once daily, can be increased to a maximum of 20 mg daily if needed. Dose adjustments should be made in increments of 5 mg and at intervals of at least two weeks.
{Chronic stable angina} (chest pain): Initial dose of 5 mg once daily, can be increased to a maximum of 20 mg daily if needed.
{Heart failure}: Initial dose of 1.25 mg once daily, increased gradually based on patient tolerance and response. Maximum dose of 10 mg daily.
{Atrial fibrillation} (irregular heartbeat): 2.5-10 mg daily, depending on the severity of the condition and patient response.
{Supraventricular tachycardia} (rapid heart rate originating in the upper chambers of the heart): Dosage depends on the individual patient and severity, consult a healthcare professional.
{Post-myocardial infarction} (heart attack) management: Initial dose of 1.25 mg once daily, increased gradually based on patient tolerance and response. Maximum dose of 10 mg daily.

Dosage Forms and Strengths:

Tablets: 5 mg, 10 mg

Administration Instructions:

Take {Bisoprolol} orally with or without food, usually once daily in the morning Swallow the tablet whole, do not crush or chew

Adverse Reactions and Side Effects:

{Fatigue} (common): Feeling tired or weak {Dizziness} (common): Lightheadedness or feeling faint {Hypotension} (low blood pressure) (less common): Abnormally low blood pressure {Bradycardia} (slow heart rate) (less common): Slower than normal heart rate {Shortness of breath} (rare): Difficulty breathing {Depression} (rare): Persistent feelings of sadness or hopelessness
Contraindications:
Known hypersensitivity to {Bisoprolol} or any of its ingredients Severe {bradycardia} Heart block greater than first degree {Cardiogenic shock} {Decompensated heart failure} Patients with severe {pulmonary hypertension}

Drug to Drug Interactions:

{Clonidine} ({Catapres}): Abrupt withdrawal of {Clonidine} while taking {Bisoprolol} can lead to increased blood pressure {Calcium channel blockers} (such as {Verapamil} [{Calan}, {Isoptin}] and {Diltiazem} [{Cardizem}, {Tiazac}]): May cause severe {bradycardia}, {hypotension}, and {heart failure} {Antiarrhythmic drugs} (such as {Amiodarone} [{Cordarone}, {Pacerone}]): May increase the risk of {bradycardia}, {Digoxin} ({Lanoxin}): May increase the risk of {bradycardia} and heart block
Pregnancy:
{Bisoprolol} is classified as pregnancy category C. There is limited information on its safety during pregnancy, so it should only be used if the potential benefits outweigh the risks.

Breastfeeding:

{Bisoprolol} is excreted in breast milk in small amounts. Consult your healthcare professional before using {Bisoprolol} while breastfeeding.

Estimated Price for a 30-Day Supply:

The cost of a 30-day supply of {Bisoprolol} can vary depending on the dose, location, and pharmacy. Assuming the patient doesn’t have insurance and is utilizing a GoodRx coupon, the estimated price for a 30-day supply ranges from $10 to $20. Prices are subject to change, and it is recommended to check with your local pharmacy or use the GoodRx website/app for the most accurate and up-to-date pricing information.

Legal Disclaimer:

This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.