Front Desk: 469-391-0070
Terbutaline Medication: Uses, Dosage, and Side Effects Explained
Summary of Key Points
Terbutaline is a medication commonly used to manage breathing difficulties such as asthma, bronchospasm, and chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles in the airways, making it easier to breathe. In some cases, terbutaline is also used to delay preterm labor. Always consult your healthcare provider before starting or adjusting your dosage. You can also speak with one of our telemedicine providers to explore your treatment options.
Names of Medication
US Brand Name: Brethine
Generic Name: Terbutaline
The generic name refers to the active ingredient in the medication, while the brand name is assigned by the manufacturer. In this article, the generic name will be used in parentheses.
Pharmacologic Category
Category: Beta-2 Adrenergic Agonists
Other medications in this category include albuterol, salmeterol, and formoterol. These drugs also help relax airway muscles, improving breathing.
Terbutaline Dosage
Terbutaline is prescribed for a variety of conditions, and the dosage will depend on the specific condition being treated. Always follow your doctor’s instructions and consult a healthcare provider before making any changes to your dosage. You can also consult one of our telemedicine providers for further guidance.
Terbutaline for Asthma
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Chronic Obstructive Pulmonary Disease (COPD)
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Bronchospasm
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline During Pregnancy (Preterm Labor – Off-label Use)
Dosage: 2.5 mg to 5 mg orally, every 4 to 6 hours.
Frequency: As needed to delay labor.
Length of Treatment: Short-term use under close medical supervision.
Terbutaline for Cystic Fibrosis
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Exercise-Induced Bronchospasm
Dosage: 5 mg orally, 30 minutes before exercise.
Frequency: As needed for prevention.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Allergic Rhinitis
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Pneumonia
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Respiratory Distress Syndrome
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Terbutaline for Pulmonary Edema
Dosage: 2.5 mg to 5 mg orally, three times a day.
Frequency: Every 6 hours as needed.
Length of Treatment: As directed by your healthcare provider.
Dosage Forms and Strengths
Tablets: 2.5 mg, 5 mg
Injection: 1 mg/mL
Administration Instructions
Terbutaline can be taken orally in tablet form or administered as an injection by a healthcare provider. When taking the tablet, swallow it whole with water. It can be taken with or without food. If you miss a dose, take it as soon as you remember, but do not take two doses at once. Always follow your healthcare provider’s instructions carefully.
Terbutaline Side Effects and Adverse Reactions
Like all medications, terbutaline may cause side effects. Some are more common and mild, while others are less frequent but potentially more serious. If you experience severe side effects, contact your healthcare provider immediately or seek emergency care.
Common Terbutaline Side Effects
Tremors: Shaking or trembling, particularly in the hands.
Nervousness: Feeling jittery or anxious.
Headache: Mild to moderate headaches may occur.
Dizziness: Feeling lightheaded or unsteady.
Less Common Terbutaline Side Effects
Increased Heart Rate (Tachycardia): A faster-than-normal heartbeat.
Chest Pain: Discomfort or pain in the chest, which may indicate a more serious condition.
High Blood Pressure: An increase in blood pressure levels.
Rare but Serious Terbutaline Side Effects
Severe Allergic Reaction (Anaphylaxis): Difficulty breathing, swelling of the face, lips, or throat, and hives. Seek emergency care immediately.
Heart Problems: Irregular heartbeat or chest pain that could indicate a heart condition. Seek medical attention immediately.
Contraindications for Terbutaline
A contraindication is a specific condition or situation where a medication should not be used because it may cause harm. If you have any of the following conditions, you should not take terbutaline, or you should discuss it with your healthcare provider before starting the medication.
Severe Heart Disease: Terbutaline can increase heart rate and cause palpitations, which may worsen conditions like coronary artery disease or arrhythmias.
Hyperthyroidism: This condition already causes an increased heart rate and metabolism. Terbutaline may further elevate these symptoms, leading to complications.
Uncontrolled High Blood Pressure (Hypertension): Terbutaline can raise blood pressure, which may be dangerous for individuals with hypertension.
Diabetes: Terbutaline can raise blood sugar levels, making it harder to manage diabetes.
Seizure Disorders: Terbutaline may lower the seizure threshold, increasing the risk of seizures in individuals with epilepsy or other seizure disorders.
Drug to Drug Interactions
Terbutaline can interact with other medications, potentially increasing side effects or reducing its effectiveness. It’s important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements, to avoid any harmful interactions.
Beta-blockers
Medications such as propranolol (Inderal) or metoprolol (Lopressor) may counteract the effects of Terbutaline, as they work in opposite ways on the heart and lungs. This interaction can reduce Terbutaline’s ability to open the airways, making it less effective for conditions like asthma or bronchospasm.
Diuretics
Drugs like furosemide (Lasix) can increase the risk of low potassium levels (hypokalemia) when taken with Terbutaline. This can lead to complications, particularly in patients with respiratory conditions who are already at risk for electrolyte imbalances.
Tricyclic Antidepressants
Medications such as amitriptyline (Elavil) may raise the risk of heart-related side effects when combined with Terbutaline. This interaction can cause an increased heart rate or other cardiovascular issues. Be sure to consult your healthcare provider if you are taking these medications.
Monoamine Oxidase Inhibitors (MAOIs)
Drugs like phenelzine (Nardil) or selegiline (Eldepryl) can also heighten the risk of cardiovascular side effects when used with Terbutaline. These medications may amplify Terbutaline’s effects on the heart, potentially leading to complications.
Terbutaline in Pregnancy
Is it safe to take Terbutaline during pregnancy?
Terbutaline is sometimes used to delay preterm labor, but its use during pregnancy is a subject of debate. The FDA has issued warnings against using Terbutaline for extended periods (beyond 48-72 hours) during pregnancy due to potential risks to both the mother and baby, including heart problems and low blood sugar in newborns. If you are pregnant and considering Terbutaline, it’s essential to discuss the risks and benefits with your healthcare provider. Our telemedicine team is available to help you evaluate your options and provide guidance on safe treatments during pregnancy.
Terbutaline while Breastfeeding
Is it safe to take Terbutaline while breastfeeding?
There is limited information on the safety of Terbutaline during breastfeeding. While small amounts of the drug may pass into breast milk, it is generally considered safe for short-term use. However, it’s important to consult your healthcare provider before using Terbutaline while breastfeeding to ensure it’s the best choice for you and your baby. Our telemedicine providers are here to discuss your specific situation and help you make an informed decision.
Estimated Cost of Terbutaline Medication
The cost of a 30-day supply of Terbutaline without insurance can vary depending on the pharmacy and location. With a GoodRX coupon, the price typically ranges from $15 to $30 for a 30-day supply. Be sure to check with your pharmacy for the most accurate pricing, and consider using a coupon to save on your prescription.
Possible Alternatives to Terbutaline
If Terbutaline is not the right option for you, there are alternative treatments and lifestyle changes that may help manage your condition. Always discuss these alternatives with your healthcare provider before making any changes to your treatment plan. Our telemedicine providers are available to help you explore these options.
Asthma
Alternatives include inhaled corticosteroids (e.g., fluticasone), long-acting beta-agonists (e.g., salmeterol), or leukotriene modifiers (e.g., montelukast). Lifestyle changes, such as avoiding triggers and using air purifiers, may also help manage asthma symptoms.
Chronic Obstructive Pulmonary Disease (COPD)
Other medications include long-acting bronchodilators (e.g., tiotropium) and inhaled corticosteroids. Quitting smoking and participating in pulmonary rehabilitation are crucial lifestyle changes for managing COPD.
Bronchospasm
Inhaled short-acting bronchodilators like albuterol or ipratropium may be used as alternatives to Terbutaline. Avoiding known triggers can also help reduce the frequency of bronchospasms.
Preterm Labor
Other medications, such as nifedipine or magnesium sulfate, may be used to delay labor. Bed rest and staying hydrated are common non-medication approaches to managing preterm labor.
Cystic Fibrosis
Treatments may include inhaled antibiotics, mucolytics like dornase alfa, and chest physiotherapy to help clear mucus from the lungs. While Terbutaline may be considered in some cases, other treatments are often preferred.
Exercise-Induced Bronchospasm
Alternatives include using a short-acting bronchodilator like albuterol before exercise. Warming up before physical activity and avoiding cold air may also help prevent exercise-induced bronchospasm.
Allergic Rhinitis
Antihistamines (e.g., loratadine) or nasal corticosteroids (e.g., fluticasone) can be used as alternatives. Reducing exposure to allergens is a key lifestyle change for managing allergic rhinitis.
Pneumonia
Antibiotics are the primary treatment for bacterial pneumonia. Rest, staying hydrated, and using a humidifier can help manage symptoms and support recovery.
Respiratory Distress Syndrome
In newborns, surfactant therapy and oxygen support are common treatments. In adults, mechanical ventilation may be necessary to manage severe respiratory distress syndrome.
Pulmonary Edema
Diuretics like furosemide and oxygen therapy are common treatments for pulmonary edema. Reducing salt intake and managing underlying conditions, such as heart failure, can help prevent pulmonary edema.
Recent Updates on Terbutaline Research
Ongoing research on Terbutaline continues to explore its safety and effectiveness, particularly in the context of preterm labor. Recent studies have highlighted the risks associated with long-term use during pregnancy, leading to updated guidelines that recommend limiting its use to short-term situations. Additionally, researchers are investigating the potential benefits of Terbutaline in treating other respiratory conditions, such as cystic fibrosis and severe asthma, though more studies are needed to confirm these findings.
It’s important to stay informed about the latest research and discuss any concerns with your healthcare provider. If you have questions about Terbutaline or are considering it as part of your treatment plan, our telemedicine providers are here to help you navigate your options and make informed decisions about your health.
