Medication Profile: Exemestane

Summary or Key Points

Exemestane, also known as Aromasin, is primarily used for treating certain types of breast cancer in postmenopausal women. This medication works by reducing estrogen levels in the body, which can help to slow or stop the growth of certain breast cancers. Consult with a healthcare provider before starting Exemestane and discuss any concerns with them.

Names of Medication

US Brand Name: Aromasin
Generic Name: Exemestane

‘Generic name’ refers to the official medical name of the drug. This is the name of the active ingredient (Exemestane), which is in parenthesis.

Pharmacologic Category

Exemestane belongs to the class of drugs known as aromatase inhibitors. Other medications in this category include Anastrozole (Arimidex) and Letrozole (Femara).

Dosing

Indication:
Early and advanced breast cancer in postmenopausal women
Dose: 25 mg
Frequency: Once daily
Length of treatment: Until disease progression

Always consult your healthcare provider before adjusting your dose. To discuss your dose or to ask any questions, you can schedule a telemedicine appointment with one of our providers.

Dosage Forms and Strengths

Exemestane is available in a 25 mg oral tablet.

Administration Instructions

Take Exemestane once daily after a meal, around the same time each day. If you miss a dose, do not take an extra dose to make up for the one you missed. Instead, take the next dose at the usual time.

Adverse Reactions and Side Effects

Common side effects include hot flashes, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhea, dizziness, and trouble sleeping. Contact your healthcare provider if these symptoms persist or worsen.

Contraindications

‘
Contraindications’ are conditions or factors that serve as a reason to withhold a certain medical treatment due to the harm that it could cause the patient. Exemestane is contraindicated in individuals who are allergic to it or any of its ingredients, as this could lead to a severe allergic reaction.

Drug to Drug Interactions

Some medications that may interact with Exemestane include estrogen products (like ethinyl estradiol, conjugated estrogens), estrogen blockers (tamoxifen), and certain types of medications used to treat chronic conditions, such as St. John’s wort or rifamycins (rifabutin, rifampin).

Exemestane in Pregnancy

Exemestane is not recommended during pregnancy. It could cause harm to an unborn baby. Consult with a healthcare provider for more information.

Exemestane while Breastfeeding

It is not known whether Exemestane passes into breast milk. Consult with a healthcare provider before breastfeeding while taking this medication.

Estimated Cost of Medication

The estimated cost of a 30-day supply of Exemestane without insurance, using a GoodRX coupon, is around $90 to $100. Prices may vary based on the pharmacy and location.

Possible Alternatives

Alternative treatments for early and advanced breast cancer in postmenopausal women may include other aromatase inhibitors (Anastrozole, Letrozole), selective estrogen receptor modulators (Tamoxifen), or different types of therapies like chemotherapy or radiation therapy. Lifestyle changes such as maintaining a healthy weight, exercising regularly, and consuming a balanced diet can also support overall health. Please discuss any treatment changes with a healthcare provider. You can schedule a telemedicine appointment with one of our providers for a detailed discussion.

Recent Updates on Exemestane Research

Recent research continues to validate the effectiveness of Exemestane in treating postmenopausal women with hormone-receptor-positive early breast cancer. Studies are also examining its potential use in reducing the risk of breast cancer in high-risk postmenopausal women. Always consult with your healthcare provider to understand the latest research and how it may apply to your treatment.

Remember, it is important to have open and regular conversations with your healthcare provider about your medication, its side effects, and any concerns or questions you may have. Our team of healthcare providers is available for immediate consultation through our telemedicine services.

Brief Legal Disclaimer: This article is for informational purposes only and not intended as medical advice. Always consult a healthcare professional for diagnosis and treatment. Reliance on the information provided here is at your own risk.