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Anthralin Cream: A Comprehensive Guide for Skin Condition Treatment
Summary of Key Points
Anthralin is a topical medication commonly used to treat skin conditions such as psoriasis, eczema, and dermatitis. It works by slowing the growth of skin cells and reducing inflammation. Typically available as a cream or ointment, Anthralin can sometimes cause skin irritation, so it’s important to follow your healthcare provider’s instructions carefully. For personalized advice on using Anthralin for psoriasis or other conditions, consider consulting one of our telemedicine providers.
Names of Medication
US Brand Name: Dritho-Scalp (Anthralin)
The name in parentheses is the generic name of the medication. The generic name refers to the drug’s chemical composition, while the brand name is assigned by the manufacturer.
Pharmacologic Category
Topical Antipsoriatic Agents
Topical Keratolytics
Dosing Instructions for Anthralin
Anthralin is used to manage various skin conditions, and the dosage and frequency will depend on the specific condition being treated. Always adhere to your healthcare provider’s instructions and consult them before making any changes to your dose. You can schedule a telemedicine visit with us for personalized guidance on how to apply Anthralin cream.
Psoriasis Treatment
Apply a thin layer to the affected areas once daily. Leave it on for 10-30 minutes, then wash off. The duration of treatment will vary based on your response to the medication.
Eczema
Apply a thin layer to the affected areas once daily. Leave it on for 10-20 minutes, then wash off. The length of treatment will depend on the severity of your condition.
Dermatitis
Apply once daily to the affected areas. Leave it on for 5-15 minutes, then wash off. The duration of treatment may vary.
Lichen Planus
Apply once daily to the affected areas. Leave it on for 10-30 minutes, then wash off. The treatment duration will depend on your response.
Vitiligo
Apply a thin layer to the affected areas once daily. Leave it on for 5-10 minutes, then wash off. The length of treatment will vary.
Alopecia Areata
Apply once daily to the affected areas. Leave it on for 10-20 minutes, then wash off. The duration of treatment will depend on your response.
Seborrheic Dermatitis
Apply once daily to the affected areas. Leave it on for 5-15 minutes, then wash off. The treatment length may vary.
Folliculitis
Apply once daily to the affected areas. Leave it on for 10-20 minutes, then wash off. The duration of treatment will depend on your response.
Prurigo Nodularis
Apply once daily to the affected areas. Leave it on for 10-30 minutes, then wash off. The treatment duration will vary.
Actinic Keratosis
Apply once daily to the affected areas. Leave it on for 5-15 minutes, then wash off. The length of treatment may vary.
Dosage Forms and Strengths of Anthralin
Cream: 0.1%, 0.25%, 0.5%, 1%
Ointment: 0.1%, 0.25%, 0.5%, 1%
Scalp Solution: 0.2%, 0.5%
Anthralin Cream Application Instructions
Apply Anthralin to clean, dry skin. Be careful to avoid healthy skin, as the medication may cause irritation. After applying, wash your hands thoroughly to prevent accidental contact with other areas. For scalp use, part your hair to ensure the medication reaches the skin. Leave Anthralin on for the prescribed time, then wash it off with lukewarm water. Avoid contact with your eyes, mouth, and other sensitive areas. If irritation occurs, contact your healthcare provider immediately. You can schedule a telemedicine visit with us to discuss any concerns about Anthralin’s side effects or application process.
Adverse Reactions and Side Effects of Anthralin
Skin Irritation (Common): Redness, itching, or burning at the application site.
Discoloration (Common): Temporary staining of the skin, hair, or nails.
Allergic Reaction (Rare): Rash, swelling, or difficulty breathing. Seek medical attention immediately if these symptoms occur.
Severe Skin Irritation (Rare): Blistering, peeling, or severe redness. Contact your healthcare provider if you experience these symptoms.
Contraindications for Anthralin Use
A contraindication is a specific situation or condition where a medication should not be used because it may cause harm. For Anthralin, certain conditions make its use inadvisable due to the potential for adverse effects.
Hypersensitivity to Anthralin
If you have a known allergy to Anthralin or any of its ingredients, using this medication could trigger a severe allergic reaction, including rash, swelling, or difficulty breathing.
Acute or Inflamed Psoriasis
Anthralin is not recommended for use on actively inflamed or irritated skin, as it may exacerbate the condition and lead to further irritation.
Ulcerated or Broken Skin
Applying Anthralin to open wounds or ulcerated skin can cause significant irritation and may delay healing.
Severe Renal (Kidney) Impairment
Anthralin is not recommended for individuals with severe kidney problems, as the medication may be absorbed through the skin and could potentially worsen kidney function.
Drug to Drug Interactions
Drug interactions occur when one medication influences the effectiveness or side effects of another. Since Anthralin is primarily used as a topical treatment for psoriasis, it tends to have fewer systemic interactions compared to oral medications. However, it’s still important to be mindful of potential interactions when using Anthralin cream.
Topical corticosteroids (e.g., Hydrocortisone, Betamethasone): Using corticosteroids alongside Anthralin may reduce the effectiveness of both treatments. It’s recommended to apply them at different times or consult your healthcare provider for alternative treatment strategies.
Salicylic acid (e.g., Salex, Neutrogena T/Sal): Salicylic acid can increase skin irritation when used with Anthralin, particularly in individuals with sensitive skin or those prone to irritation.
Other topical irritants (e.g., Benzoyl peroxide, Retinoids): Combining Anthralin with other topical medications that may cause irritation can lead to excessive redness, peeling, or discomfort.
Anthralin in Pregnancy
Is it safe to use Anthralin during pregnancy?
There is limited information on the safety of Anthralin use during pregnancy. Since it is a topical medication, the amount absorbed into the bloodstream is generally minimal. However, as a precaution, it’s advised to avoid using Anthralin during pregnancy unless the potential benefits clearly outweigh the risks. Always consult your healthcare provider before starting or continuing Anthralin if you are pregnant. If you are pregnant or planning to become pregnant, our telemedicine providers can help you evaluate safe treatment options.
Anthralin while Breastfeeding
Is it safe to use Anthralin while breastfeeding?
There is no definitive evidence on whether Anthralin passes into breast milk. However, because it is applied topically, the risk to a breastfeeding infant is likely low. If you are using Anthralin while breastfeeding, avoid applying it to areas that may come into direct contact with your baby, such as the chest. Always consult your healthcare provider before using Anthralin while breastfeeding to ensure it is safe for both you and your baby.
Estimated Cost of Anthralin Cream
The cost of a 30-day supply of Anthralin without insurance can vary depending on the pharmacy and location. With a GoodRx coupon, the price typically ranges from $30 to $60 for a 30-gram tube. Prices may fluctuate, so it’s a good idea to check with your local pharmacy or use a discount service like GoodRx for the most up-to-date pricing.
Possible Alternatives to Anthralin
If Anthralin is not suitable for you, or if you are exploring other treatment options, several alternatives are available depending on the condition being treated. Always discuss these alternatives with your healthcare provider before making any changes to your treatment plan. Our telemedicine providers are available to help you explore these options.
Psoriasis: Alternatives include topical corticosteroids, vitamin D analogs (e.g., Calcipotriene), phototherapy, or biologic medications such as Adalimumab (Humira) or Etanercept (Enbrel).
Eczema: Treatment options include moisturizers, topical corticosteroids, calcineurin inhibitors (e.g., Tacrolimus), and lifestyle changes such as avoiding triggers and using gentle skincare products.
Dermatitis: Managing dermatitis often involves avoiding irritants, using emollients, and applying topical corticosteroids or antihistamines to reduce inflammation and itching.
Lichen Planus: Treatment options include topical corticosteroids, oral antihistamines, or immune-modulating treatments such as Tacrolimus or systemic corticosteroids.
Vitiligo: Alternatives include topical corticosteroids, calcineurin inhibitors, phototherapy, or depigmentation therapy for more extensive cases.
Alopecia Areata: Treatment options include topical corticosteroids, minoxidil (Rogaine), or immunotherapy treatments such as diphencyprone (DPCP).
Seborrheic Dermatitis: Antifungal shampoos (e.g., Ketoconazole), topical corticosteroids, or calcineurin inhibitors are commonly used to manage this condition.
Folliculitis: Treatment may involve topical or oral antibiotics, antiseptic washes, and avoiding tight clothing or shaving the affected area.
Prurigo Nodularis: Options include topical corticosteroids, antihistamines, or phototherapy to help reduce itching and inflammation.
Actinic Keratosis: Treatment options include cryotherapy, topical treatments such as 5-fluorouracil (Efudex), or photodynamic therapy to remove precancerous lesions.
Recent Updates on Anthralin Research
Recent research on Anthralin has focused on improving its delivery and reducing side effects like skin irritation. Scientists are exploring new formulations, including liposomal and nanoparticle-based systems, to enhance the medication’s effectiveness while minimizing irritation. Additionally, studies are investigating the use of Anthralin in combination with other therapies, such as biologics, to improve outcomes for patients with psoriasis and other skin conditions. While these developments are promising, more research is needed to confirm their long-term benefits. If you are interested in learning more about new treatment options or participating in clinical trials, our telemedicine providers can help guide you through the latest research.
